Ma Qi Capsules Compound Of BNP In Patients With Left Ventricular Hypertrophy And Cardiac Function

Objective:To study the compound capsule of Qi Deficiency Qi Ma phlegm hypertensive left ventricular hypertrophy(LVH) in patients with plasma brain natriuretic peptide(BNP) and its possible mechanism.Methods:58 cases of hypertension in patients with left ventricular hypertrophy(Qi-deficiency and phlegm type) were randomly divided into two groups,treatment group 30 cases,28 cases of the control group,two groups are taking benazepril(Lotensin) + amlodipine(Luo live-hi) blood pressure, treatment group taking capsules of compound stilbazolium Ha,were treated for 12 weeks.Observation of clinical symptoms before and after treatment,blood pressure,left ventricular mass index and changes in BNP,and a comparative analysis of statistical methods.Results:1,the treatment group in improving the BNP have a better than the control group.BNP before and after treatment both groups improved(p＜0.05) but the treatment group than the control group(p＜0.05).2,the treatment group to improve the clinical symptoms more obvious than in the control group. Selected the total effective rate of clinical symptoms according to the size of order as follows:weak＞shortness of breath＞the first re-＞stun＞headache＞chest.In which dizziness,weak inter-group comparison has a very significant difference(P＜0.01).To improve the symptoms of the treatment group was superior to the control group,between the two groups were significantly different.3,the treatment group have a better role in regulating blood pressure.Two groups of patients after treatment than before treatment of blood pressure were significantly reduced blood pressure clinic observation prompted the efficiency of the treatment group was 56.7%,total effective rate was 90%;the efficiency of the control group was 53.6%,total effective rate was 78.6%,the treatment group than the control group(p＜0.05).Self-test by recording changes in blood pressure,medication two weeks after the two pre-treatment systolic blood pressure decreased significantly more(P＜0.05), contrast is not very different between groups(p＞0.05);diastolic pressure, the treatment group than in pre-treatment significantly decreased(p＜0.05), no significant decline in the control group(p＞0.05).12 weeks after treatment, systolic and diastolic blood pressure between the comparison group were significantly different(p＜0.05).On the circadian rhythm of blood pressure is concerned,the two groups before and after treatment of blood pressure rhythms are more marked improvement(P＜0.05);the treatment group than the control group(P＜0.05).4,the treatment group in the improvement of left ventricular mass index(LVMI) better than the control group.Comparison of the two groups before and after before and after treatment are significantly lower(P＜0.05),groups are better than the treatment group compared the control group(P＜0.05).Conclusion:The Compound Effect of Qi-deficiency and phlegm Ma capsule left ventricular hypertrophy in hypertensive patients with marked improvement in clinical symptoms,control blood pressure,reducing left ventricular mass index and the role of BNP.