A Clinical Study On The Treatment Of Nonalcoholic Steatohepatitis In The Liver Function ALT,AST,GGT With Shuganjianpi Qingrelishi Method

Title:A Clinical Study on the Treatment of Liver Depression Spleen Deficiency And Blood Stasis Damp-heat Stagnation Syndrome type of non-alcoholic steatohepatitis in the liver function with Shuganjianpi Qingrelishi method.Objective:Through collecting clinical cases,to investigate Shuganjianpi Qingrelishi method of the treatment of NASH clinical efficacy and to analyze the effect of Chinese medicine on the treatment of NASH in the liver function(ALT,AST,γ-GT),thus to provide new ideas and treatment methods for the treatment of NASH.Methods:1,To seclect 80 cases patients with Non-alcoholic steatohepatitis diseases who from May 2007 to May 2008 in the number one hospital of Heilongjiang Province Chinese medicine university inpatient and outpatient.The patients with NASH as the Chinese medicine theory is liver depression spleen deficiency and blood stasis damp-heat stagnation syndrome,and conforming to western medicine diagnose criterion.The patients were randomly divided into treatment group 40 cases,the control group 40 cases.Patients in the two group by gender,age,duration,symptoms tested at compared.There was no significant difference(P＞0.05),and comparabil-ity.2,The treatment group take the Chinese medicine theory as the instruction,and based on the principle of Shuganjianpi Qingrelishi method.The control group adoption Dongbao Gantai tablet treatment 3,In the course of treatment,the items that we had observed with all patients were glutamic pyruvic transaminase(ALT),glutamic oxaloacetic transaminase(AST),γglutamyltransferase(γ-GT),and do statical analysis, and compare the results.Result:The total effective rate of improvement the function of liver of Chinese medicine in the treatment group is 89.47%after treatment,while it is 79.49%in the control group,the difference between the two groups is not significant,but there was significant difference in the level of ALT, AST,andγ-GT.between the two group,the level of ALT trial group is 47.11±17.27,while the conrtol group is 66.51±18.31(P＞0.05);the level of AST trial group is 40.76±15.60,while the conrtol group is 58.10±14.94 (P＞0.05);the level of GGT trial group is 38.084-14.99,while the conrtol group is 56.10±14.54(P＞0.05).During the period of the clinical study has not adverse events and adverse reaction occured.Conclusion:the Treatment of non-alcoholic steatohepatitis with Shuganjianpi Qingrelishi Method could improve the function of liverALT,AST,γ-GT,the effect is superior to the conrtol group.The clinical study is good safety.