The Study On The Blood Viscosity And Blood Gas Variations And Their Relativity After Traumatic Brain Injury In Rats

Objective:to observe blood viscosity and blood gas variations after the rats' brain trauma were percussed by heavy free-falling,and seek its change discipline and reason for clinical treatments and hematology factor of secondary trauma.Methods:Use weights-free-falling brain injury model to cause brain injury and take out mixed venous blood from right atrium to detect blood viscosity and blood gas variations by blood viscograph and blood-gas analysis meter.Results:1.The blood viscosity of high-low Shear rate of brain trauma rats group was significant higher the control(P＜0.05),and blood viscosity appeared peak after they had injured for 30 minutes and one day and seven days respectively,then the blood viscosity appeared platykurtosis after they had injured for eight hours and five days.2.The blood pH value and PCO₂ and PO₂ were different with rats keeping different times after they injured.The pH value hoisted after they injured for several minutes,and dropped to platykurtosis after 30 minutes and one day,and then appeared peak at six hours and tow days,and then went to dropoff;The PCO₂ appeared peak at thirty minutes and one day separately,and then appeared platykurtosis at six hours and tow days,and afterwards it went down then tend to platykurtosis;The PO₂ went up at ten minutes,and then went down gradually,and went to platykurtosis at 12 hours,and afterwards went up slowly.Conclusion:1.The brain trauma could make rats blood viscosity increase,moreover appeared peak after they injured for thirty minutes and one day and seven days separately.2.The brain trauma could cause pH value to drop,and appeared platykurtosis at thirty minutes and one day separately.3.The brain trauma could make PCO₂ rise,and appeared peak at thirty minutes and one day separately.4.The brain trauma could cause PO₂ to drop,and appeared platykurtosis at 12 hours.5.The blood viscosity variations was obvious relativity with the blood gas variations.6.The blood viscosity and blood gas variations may was relativity with secondary variations after traumatic brain injury.