Clinical Observation Of The Method Of Cooling Blood And Promoting Blood Flow On Treating Systemic Lupus Erythematosus

Objective: 1.To explored in the method of cooling blood and promoting blood flow of drugs in the treatment of stagnated heat and blockage card of systemic lupus erythematosus; 2.The evaluation of the treatment methods used for simple MP + cyclophosphamide are attenuated synergies; 3.For the treatment of stagnated heat and blockage card of systemic lupus erythematosus provide the basis for stasis.Methods: Collected to meet the requirements of a total of 40 cases of cases,in accordance with the principle of stochastic control,40 cases were divided into treatment and control groups. Patient groups are in line with the diagnostic criteria for stagnated heat and blockage card of systemic lupus erythematosus. In the conventional treatment group on the basis of traditional Chinese and western medicine treatment with the use of cooling blood and promoting blood flow role of the traditional Chinese medicine treatment, the control group using conventional western medicine treatment,patients were observed in patients hospitalized for treatment before and three months after the clinical symptoms and signs and the related laboratory tests such as: white blood cell, platelet, hemoglobin, urine protein, anti-ds-DNA, anti-SSA antibody, anti-SSB antibodies, anti-Sm antibodies, complement C3, C4, 24h urinary protein, ESR, C-reactive protein, liver and kidney function. Information SPSS14.0 software used for statistical analysis. Results: 1. The treatment group effect of the disease have assessed the overall efficiency of the control group, but the difference was not statistically significant (p> 0.05); 2. The treatment group and control group SLEDAI score and traditional Chinese medicine symptoms score before treatment than after treatment are significantly improved (P <0.01), and the treatment group significantly lower than the control group, there is significant difference (P <0.05); 3. Treated the two groups complement C3, C4 were increased before treatment, with significant difference (P all <0.01), the treatment group's C3 complement increased significantly than the control group's (P <0.05); after treatment the two groups CRP, ESR lower than before treatment, but treatment group's CRP significantly lower than the control group, with significant difference (P all < 0.05). After treatment treatment group's IgG reduce the more obvious than the control group, with significant difference (P <0.05); 4. The 24-hour urinary protein of the treatment group was significantly lower than the control group before and after the treatment, but no significant difference (P> 0.05 ); 5. After treatment the number of positive cases of two groups of anti-ds-DNA antibodies has reduced than pre-treatment (P all <0.05), however, no difference in the two groups after treatment (P all> 0.05); the group of anti-SSA antibody, anti-SSB antibodies, anti-Sm antibodies before and after treatment there was no significant difference (P all> 0.05).Conclusion: Western medicine treatment combined with cooling blood and promoting blood flow of drugs in the treatment of stagnated heat and blockage card of systemic lupus erythematosus can improve the clinical symptoms, control SLE activity, reduce proteinuria and reduce side effects. The effect of Traditional Chinese combined with western medicine was better, and this study for clinical treatment of stagnated heat and blockage card of systemic lupus erythematosus provides a frame of reference.