| Objective To find out whether there are long-term injuries to the infants' liver and kidney function caused by melamine.Methods Make a follow-up visit to the patients who have been diagnosised melamine related urinary calculus. Write down the original datas before treatment, including general conditions, consuming milk powder, routine urine test, liver and kidney function and serum electrolytes, B-ultrasonography.Give treatments to them.The period is one year. Review the patient's routine urine test, liver and kidney function and blood serum electrolyte, the urinary system B-ultrasonography after one year later.Evaluate initially whether there are long-term injuries to the infants'liver and kidney function caused by melamine according to the results.Results All 37 cases before treatment were suffering from kidney stones, yet there were only 3 cases still had kidney stones after treatment, the statistical analysis was P<0.05, which meant that most of the patients'urinary calculus disappeared; The statistical comparision of urine occult blood before treatment and after treatment was significant with P<0.05, so was the urine leukocyte.That meant urine routine improved significantly. Respectively, before treatment the serum creatinine(SCr),serum uric acid(UA)and serum glutamic pyruvic transaminase(ALT) was higher than that after treatment with P<0.05,which meant that the liver and kidney function recovered very well. The serum urea nitrogen(BUN) before treatment was not significantly different with that after treatment with P>0.05.The same to the serum glutamic-oxaloacetic transaminase (AST). It meant there were no significant changes to BUN and AST. The serum kalium before treatment was not significantly different with that after treatment (P>0.05),but the serum calcium after treatment was higher than that before treatment with P<0.05.Conclusion There was no obvious long-term injury to the infants'liver and kidney function caused by melamine.
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