1:1 Case-control Study On Related Factor Of Thyroid Cancer

Objective:Pass to deliver the investigate of related and dangerous factor of thyroid cancer analysis at first to Dalian City, inquiry into influence to deliver the related factor of thyroid cancer outbreak at first, provide for the prevention and cure which delivers thyroid cancer at first basis.Method:Adopt 1:1 case-control study, selected from January 2008 to December 2009 between the Zhongshan Hospital of Dalian University of hospitalization for thyroid cancer surgery and were histologically diagnosed as thyroid cancer, a total of 200 cases. At the same time in accordance with the principle of 1:1 matching, non-cancer hospital in the same period, non-thyroid, breast-related diseases,200 patients were selected. Matching conditions:the same sex, age±3 years.200 pairs of thyroid carcinoma patients and controls using the unified design of the questionnaire, by trained investigators on the case and control himself face to face surveys. The contents which investigates form mainly includes:the general circumstance,living environment-. life behavior. food habit,social psychological factors,female reproductive history. disease history,household history etc. Available information, enter the Excel table to establish a database, and adopt SPSS11.5 and SAS8.0 statistical software used to analyze, Primarily on the basis of single factor analysis of the types of information using x2 test, rank sum test and single factor condition logistic regression analysis, multivariate analysis using multivariate condition logistic regression analysis.Result:Univariate analysis showed that high levels of education, place of residence for the city, heavy as ten years ago, more consumption of seafood, seaweed, and pickled foods class, maternal age, too, have long- term use of estrogen drugs, early pregnancy early age, high education, with a family history of thyroid disease and other cancers such as thyroid cancer risk factors. Psychological factors, often feel pressure, love sulk, failing to do not want to talk with people, biased pessimistic attitude, marriage discord, and harmony with people without risk factors for thyroid cancer. On the preliminary selection of and factors related to thyroid cancer Multivariate condition logistic regression analysis, the results showed that heavy as ten years ago, pickled food, seafood, kelp intake of too much class and work life often feel the pressure, love sulk for the thyroid cancer risk factors.Conclusion:The Dalian City delivers the occurrence of thyroid cancer and gets in touch with education,intake of seafood and marine vegetables,love sulk and easygoing is closely related to such factors...