Study Of The Relationship Among Ambulatory-Aterial Stiffness Index For Extracranial And Intracranial Arterial Stenosis

Objective:To investigate the relationship among ambulatory aterial stiffness index(AASI)and risk factors of ischemic stroke and intracranial and extracranial arterial stenosis,and to evaluate the relationship among AASI and the extent and sites of intracrania arterial stenosis and the number of relevance to guide clinical prevention.Methods:To collect 104 patients with ischemic stroke patients during from July in 2008 to December in 2009 at the First Affiliated Hospital of Chifeng College, all patients underwent CT angiography (CTA) or magnetic resonance angiography (MRA), carotid artery color Doppler ultrasound (CDUS), Transcranial Doppler (TCD) to determine whether there is intracranial arterial stenosis or Extracranial artery stenosis.Extracranial artery stenosis according to North American symptomatic carotid artery stenosis testing method (NASCET) were divided into four groups:normal, mild stenosis, moderate stenosis, severe stenosis.Intracranial arterial ste-nosis according to TCD peak systolic flow velocity divided into four groups: normal,mild stenosis,moderate stenosis, severe stenosis.The number of branch of patients with stenosis were divided into non-restenosis group, one vessel stenosis group, two artery stenosis group, three or more vascular stenosis. Risk factors were recorded such as age,gender, history of dia-betes,hematological indicators of low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and measure height, weight, calculate body mass stiffness index (BMI) and ambulatory-aterial stiffness index (AASI).Results1.It was no statistical difference between extracranial arterial stenosis and AASI.2.It was statistical difference (P<0.05)between intra- cranial artery stenosis and AASI.It was statistical difference(P<0.05) between severe stenosis and other groups.3.AASI was statistical difference (P<0.05)between the normal group and other vascular stenosises, AASI of blood vessels narrow is more than the normal group. However, there was no significant difference between one lesions group, and two lesions group, three or more lesions group with other vascular stenosises, there are statistically significant(P<0.05).Conclusion:AASI has nothing to do with extracranial arterial stenosis, and related severe intracranial artery stenosis.