Investigation Of Vitreous Levels Of MCP-1 In The Patients With Proliferative Diabetic Retinopathy

ObjectiveTo detect the Vitreous levels Of MCP-1 in the patients with proliferative diabetic retinopathy and the role MCP-1 plays in the development of DR.MethodsThe Vitreous levels Of MCP-1 in 22 patients with PDR (experimental group) were detected by ELISA,and then compared with which in 2 normal subjects (normal control) and 15 patients with RD (disease control).ResultsThe levels of MCP-1 in experimental group was (1316.85±286.402)μg/ml. It was significantly higher than which in the disease control groups (652.15±410.375)μg/ml and in the normal control groups (182.60±77.631)μg/ml (p< 0.01)ConclusionsHigh expression of MCP-1 in PDR patients suggesting that MCP-1 involved in the DR process. It may be the part of the DR startup process, or to start one, and through to the end.