The Pharmaceutical Study Of Kun Le Effervescent

Kun Le effervescent tablet is made of traditional Chinese medicine Sophora flavescens and Cnidium preparation, their prescription is:Sophora alkaloids 90 g, Osthol 30 g, lactose 180g, sodium bicarbonate 92 g, and citric acid 120 g. after many experiments prove that Kun Le effervescent has heat dampness, itching of the efficacy of insecticide. Bet for the hot and humid due to vaginal itching, burning, and vaginal discharge embolism. Kun Le effervescent is a traditional Chinese medicine theory and clinical practice of modern scientific research techniques and the product of a combination of research, with heat dampness, the efficacy of insecticideThis research project is under the premise of the clinical efficacy and reliable, according to the nature of the prescription medicines to establish Kun Le Effervescent process routes and process conditions, and set quality standards, at the same time the stability test. The results show that small-batch trial:The preparation process is reasonable, feasible, quality control, product properties and stability. This study were optimized using orthogonal design the best preparation process, right-Kun Le effervescent tablets matrine, matrine and Osthol oxidation carried out TLC results have special properties; use of acid-base titration Determination of an effervescent tablet Kun Le content of total alkaloids of Sophora 56.16mg; using HPLC determination of 1-Kun Le effervescent tablets osthol of 12.1440mg. And this study has been developed an effective quality control of the preparation method. This study for the standardization of the quality of effervescent fun-kun study has laid a good foundation.