AQP1 Expression In Non-small Cell Lung Cancer, And MMP-9,Ki67 Relationship Between The Expression

ob j eetive DISeuSSion of the water ehannel protein-1(AQPI)innon-Small eell lung eaneer(NSCLC)in the expreSSion and Signifieanee,as well as matrix metalloproteinase-9(MMP-9),proliferating eellnuelear antigen(Ki67)expreSSion.Methods Deteeted by inununohistoehemistry 50 eases of non-smalleell lung eaneer AQPI and MMP-9,Ki67 exPression,and randomlyseleeted 30 eases of adjaeent normal lung tissue,30 eases ofPulmonary benign masses as a eontrol.AQPI exPression analysis ofelinieal and Pathologieal features as well as MMP-9,Ki67 exPressioneorrelation.Results 1.AQPI Positive substanee loeated in the eytoPlasm and/or membrane,nueleus eoloring also see the tumor and normal tissueat the junetion of the edge inereased exPression:AQPI Protein inNSCLC,adjaeent normal lung tissue,benign tumor,the positive rate32.0%(16/50),3.3%(1/30)and 6.6%(2/30),the differenee wassignifieant(p<0.01). 2.AQPI Drotein exDression in NSCLC,sex,age, clinical stage, tumor T staging(P>O.05), and the pathological type,differentiation degree, lymph node metastasis and whether there arerecurrent metastasis(P