Diagnostic Value Of Transvaginal Contrast-enhanced Ultrasound In Small Adnexal Masses

Objective:To evaluate the diagnostic value of different diagnostic methods in small adnexal masses,especially transvaginal contrast-enhanced ultrasound(CEUS). Methods: Sixty-six patients with seventy-six small adnexal masses were examined with transvaginal two-dimensional ultrasonography(TV-2D),color doppler energy imaging(CDE) and CEUS. The test results were compared with the pathological results or long-term follow-up results.Perfusion patterns, perfusion intensity and the relationship between begin and malignant small adnexal masses were analyzed.The receiver operator characteristic(ROC) curves were established and the cut-off point was chosen. Results:Begin and malignant small adnexal masses had statistical differences in perfuse pattern and perfuse intensity. The sensitivity and specificity of perfusion patterns were 100% and 82.4% respectively (patternâ…¢a as the cut-off point). The sensitivity and specificity of perfusion intensity were 87.5% and 86.8% respectively(grade 4 as the cut-off point).The sensitivity and specificity of combining perfusion patterns and perfusion intensity to diagnose malignant small adnexal tumors were 87.5% and 95.6% respectively. Combine TV-2D with CEUS had the strongest agreement between the test result and the actual outcome among the obove methods in diagnosis of malignant small adnexal tumors, and the sensitivity and specificity were 87.5% and 97.1% respectively. Conclusion:CEUS could be used to diagnose the small adnexal masses and has definite diagnostic value to identify malignant adnexal masses.TV-2D combined with CEUS is the most cost-effective method of TV-2D,CED,CEUS used respectively or combiningly in differentiating malignant small adnexal tumors from benign small adnexal masses.