Objective: To evaluate the diagnostic of single or combined two-dimensionalcontrast-enhanced ultrasound (2D-CEUS) and three-dimensional contrast-enhancedultrasound (3D-CEUS) in small adnexal masses. Methods: Forty-three patients withforty-seven small adnexal masses were examined with contrast-enhanced two-andthree-dimensional ultrasonography. The images of Begin and malignant small adnexalmasses were compared. Sonographic findings were compared with the pathologicalresults or long-term follow-up results. Results: Begin and malignant small adnexalmasses had statistical differences in perfuse pattern, perfuse intensity and time-intensitycurve patterns. The sensitivity and specificity of combining perfuse pattern, perfuseintensity and time-intensity curve patterns to diagnose malignant small adnexal tumorswere100%and85%respectively. Begin and malignant small adnexal masses hadstatistical differences in blood vessels of envelope, perfuse pattern, separated and internalenhancement of contrast-enhanced three-dimensional ultrasound, and the sensitivity andspecificity were100%and98%respectively. The sensitivity and specificity were100%and85%,100%and98%respectively in parallel test result and in serial test result ofcombining contrast-enhanced two-with three-dimensional sonography. Conclusion:Contrast-enhanced two-dimensional sonography has an advantage in showing perfusioncharacteristics of blood flow of begin and malignant small adnexal masses.Contrast-enhanced three-dimensional sonography could display the angiographiccharacteristics of the entire small adnexal masses, and it has an advantage in displayingspace structure of the complex vascular. A combination of both contrast-enhanced two-and three-dimensional sonography has a higher diagnostic value in the diagnosis of malignant tumor in serial test. |