Clinical Research Of Nourishing Yin To Restrain Fire Preparations For Treating Yin Deficiency And Fire Redundancy Tachyarrhythmia

The research comes from NCET-07-0522.Objective:Through systematically review and prospective study to compare the clinical curative effect of all kinds of nourishing yin and restraining fire preparations for treating tachyarrhythmia. To evaluate the curative effect of all kinds of nourishing yin and restraining fire preparations for treating tachyarrhythmia.Methods: Comprehensively collecting RCTs(Randomized controlled trials)of nourishing yin to restrain fire preparations for treating tachyarrhythm- ia .Then select qualified research and assess the methodological quality of inclusive trails by Jadad scale,analyze and compare related data by Meta-analysis. Prospective study: fall the 60 patients with yin deficiency and fire redundancy tachyarrhythmia into 2 groups(treatment group n=30, control group n=30) randomly. The treatment group takes fumaianshenyin, the control group takes puluopatong. A course of treatment contains 4 weeks. To observe the symptoms, 24h dynamic electrocardiogram, the function of liver and kidney, the routine of blood, urine and dung, and adverse reactions. Results: 8 RCTs were included to test 7 Prescriptions,one assessed by Jadad scale got 4 points is classified to high-quality article,and others 1 point to low-quality articles. Total clinical curative effect and Clinical symptoms improvement were used as the standards for comparison of each research. The results of Meta-analysis show that Xinjining capsule,kuailvning capsule,Guilongnixintang and Dinglvtang are clinically effective in treating tachyarrhythmia and improving clinical symptom. Prospective clinical study shows that there's no obvious difference in the curative between the treatment group and control group. But in TCM symptoms the treatment group is better than the control group. There's no abnormal changes in the function of liver and kidney and the routine of blood, urine and bung after the cure.Conclusions: Nourishing yin and restraining fire preparations are clinically effective in treating tachyarrhythmia. And compared with western medicine it has less adverse reactions.