The Effect Of Glutamine On The Structure And Function Of Erythrocyte Membrane On Training Rats

We have observed the variation character of the training rats'erythrocyte membrane structure and function which were intervened by the glutamine for 8 weeks and studied the influence of glutamine to the training rats'erythrocyte membrane structure and function. that can enrich the application study of glutamine and provide the scientific foundation for glutamine's protection of erythrocyte membrane and prevention of exercise-induced hemolysis and anemia.We have made rats swimming training for 8 weeks and divided it into four groups which are control group, peacefully supplemented glutamine group, training group and training with supplemented glutamine group. By examining and comparing, the results of the phospholipids, the cholesterol, the glutathione, the glutathione peroxidase, the sulfhydryl, the malondialdehyde and the haemoglobin of the rats'erythrocyte membrane are as follows:1. The PH, CH content and CH/PH of RBCM: we have compared the S group with the C group, the PH of the S group is lower than that of the C group(P=0.023), the CH/ PH of the S group is higher than that of the C group (P=0.001); and the S group compared with the SG group, the PH/CH of the S group is lower than the SG group (P=0.009, P=0.006), but the CH/ PH of the S group is higher than that of the SG group (P=0.000). Those implied that the PH and CH of the RBCM can be increased by supplementing glutamine.2. The GSH content and GSH-PX activity of RBCM: we have compared the SG group with the C group, the GSH content of SG group RBCM is higher than the C group (P=0.038), but other groups haven't the significance with the C group; and the SG group compared with the S group, the GSH content of SG group RBCM is higher than the S...