N-Heterocyclic-Carbene-Palladium(Ⅱ)-1-Met Hylimidazole Complex Catalyzed α-Arylation Of Benzo Ring Ketones

α-Aryl carbonyl compounds are important structural units of many natural products, drugs and synthetic intermediates. Therefore, they have received the attention of organic chemists. The palladium catalyzed α-arylation reactions of carbonyl compounds are the main methods to the synthesis of such compounds. Typically, additional phosphine ligands are necessary in the palladium-catalyzed α-arylation reactions of carbonyl compounds. However, the highly active phosphine ligands are toxic, expensive and difficult to synthesize, thus, during the past years, much attention was turned to using the air- and thermal-stable, easily available and cheap N-heterocyclic carbene as the ligands. In this thesis, the α-arylation reactions between benzo ring ketones and aryl chlorides in the presence of a well-defined, easily available N-heterocyclic carbene-palladium(II)-1-methylimidazole [NHC-Pd(II)-Im] complex was investigated, which can be divided into two parts:1. NHC-Pd(II)-Im complex catalyzed α-arylation of 1-indanones with aryl chlorides.2. NHC-Pd(II)-Im complex catalyzed α-arylation of tetralones with aryl chlorides.