The Clinical Study On The Effect Of Boosting Qi And Nourishing Yin, Quickening The Blood And Transforming Stasis To Sncv Of Patients With Dpn

Objective:To observe the function and the possible mechanism of Tongluotangtai Poly-pharmaceutical on how to regulate and influence the DPN patients, SNCV.Method:forty patients with DPN, who were Qi-Yin deficiency as root and blood stasis as appearance, were randomly divided into the treatment group(20 cases) and the control group(20 cases) by turn. All patients were treated with the basical treatment. The patients in control group were given Methycobal, every 0.5mg,3.times. The patients in treatment group also were reveived the TCM decoction Tongluotangtai (150ml tid) with the main function of supplementing qi and nourishing yin and prompting blood circulation to dissipate blood stasis. Both groups were treated for 8 weeks.The symptoms and inflammatory factors of patients in two groups were observed before and after the treatment, including plasma concentrations of fasting blood glucemia(FPG),2hPG,HbAlc,SNCVet al.Results:The clinical curative effective of symptoms in the treatment group: obvious effective 11 cases, effective 8 cases, ineffective 1 cases, the significant effective rate was 55%,the total effective rate was 95%.Clinical syndromes and signs were significantly improved in the treatment group after treatment, including FPG, 2hPG, HbAlc, SNCV et al, while those in the control group were not significantly changed. There was a remarkable discrepancy (P<0.05) before and after the treatment in the treatment group.Conclusion:Tongluotangtai can improve clinical syndromes and reduce the inflammatory fators of patients, for example:FPG,2hBP, HbAlc. Moreover, it also can improve SNCV. It perhaps has benefits in treating patients of DPN.