| Objective:To investigate the effect of internal and external treatment with the Chinese Medicine, particularly prescription of Tongluotangtai and washing application of Tangtongwai solution, on Qi and Yin deficiency and blood stasis block syndromes of DPN patients, including clinical symptoms, nerve conduction velocity, plasma glucose, glycated serum protein and other indexes; evaluate the effect of external treatment with the Chinese Medicine on DPN patientsMethods:62patients with DPN were randomly divided into the treatment group with Chinese medicine and the control group with Western medicine. All patients were treated with the basic therapy of diabetes mellitus. The patients in treatment group were given Tongluotangtai (150m tid,3times a day,8weeks) and Tangtongwai solution washing the legs (15-20minutes, every other day) while the patients in control group were given Mecobalamine (0.5mg tid). The symptoms of patients in two groups were observed before and after the treatment, including clinical symptoms, plasma glucose, glycated serum protein, sensory and motor nerve conduction velocity, and other indexes.Results:The clinical studies show that:Treatment group, there were15cases markedly effective, effective in14cases, ineffective in1patients. The effective rate was50%, and total effective rate was96%.Control group,8cases markedly effective,15cases effective and7cases ineffective, markedly effective rate was27%, total effective rate was77%and difference was statistically significant (P<0.05). Clinical syndromes and signs were significantly improved in the treatment group, including sensory and motor nerve conduction velocity were significantly improved, plasma glucose and glycated serum protein improved.Conclusions:Internal and external treatment with the Chinese Medicine can obviously improve the clinical symtoms of DPN patients, reduce the blood sugar and glycated serum protein, improve sensory and motor nerve conduction velocity, promote the recovery of the damaged nerve. |
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