Dialectical Spraying Diarrhea-predominant Irritable Bowel Syndrome With Different Syndromes Of Efficacy And Plasma 5-ht, Mot's Impact

1,The goal1.1 Chemical application discussion on syndrome differentiation of traditional Chinese medicine treatment of IBS-D possible mechanism.1.2 Discussion blood plasma 5-HT, the MOT level is divided the significance and the value dialectically in the IBS-D Chinese medicine.1.3 Discusses IBS-D the pathogenesis and blood plasma 5-HT, the MOT level and the IBS-D diagnosis relatedness.2,The object and sideThis research has carried on the reasonable clinical research design according to the related standard.Unifies the actual situation choice to conform to the IBS-D Romeâ…¢The diagnosis standard, simultaneously conforms to the Chinese medicine weakness of spleen and stomach card or the liver prosperous spleen weakness card diagnosis standard, the age in 18-60 year-old patient, in which weakness of spleen and stomach card 60 examples, the liver prosperous spleen weakness card 60 examples, simultaneously chooses the healthy person 20 examples.The weakness of spleen and stomach card gives in Huang Qijian the soup addition and subtraction treatment, the liver prosperous spleen weakness card gives the pain to flow swiftly wants the side addition and subtraction treatment, the treatment course is 30 days.According to "Chinese native medicine New Medicine Clinical Research Guiding principle" around determined the curative effect evaluation standard, treats to the IBS-D patient carries on clinical symptom grading.Around determines the IBS-D patient to treat blood plasma 5-HT and the blood plasma MOT data, simultaneously determines healthy person blood plasma 5-HT and the blood plasma MOT data.Around mainly observes the IBS-D patient to treat the Chinese medicine card period of five days change and blood plasma 5-HT and the blood plasma MOT level change and carries on the comparison with the healthy person.3,Result3.1 Huang Qijian the soup treats the IBS-D weakness of spleen and stomach patient and the pain releases must only then treat the IBS-D liver prosperous spleen weakness patient to be able the varying degree to improve patient's symptom, also can cause the IBS-D weakness of spleen and stomach patient and IBS-D liver prosperous spleen weakness patient blood plasma 5-HT, the MOT level obvious drop tends to normally.(P<0.01)3.2 IBS-D and normal human plasma 5-HT level in patients with significant differences. (P<0.01) IBS-D patients and normal human plasma MOT level there are significant differences. (P<0.05)3.3 IBS-D of deficiency of spleen and stomach and IBS-D in patients with liver Mong 5-HT, MOT level in plasma of patients with spleen-deficiency type not significantly different.4,Conclusion4.1 Chinese medicine dialectical Shi Yaoke improves the IBS-D patient's symptom obviously, has the complex therapy function to the IBS-D patient.4.2 Application can significantly reduce IBS-D of TCM syndrome differentiation of spleen-stomach weak-and IBS-D in patients with liver Mong 5-HT, MOT level in plasma of patients with spleen-deficiency type.4.3 Blood plasma 5-HT, the MOT level prompts not obviously to IBS-D weakness of spleen and stomach patient and the IBS-D liver prosperous spleen weakness patient's Chinese medicine dialectical minute.4.4 Blood plasma 5-HT, the MOT level may take the IBS-D diagnosis the conventional assistance inspection, but must determine the IBS-D laboratory inspection value also to have the further investigation and study.