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The Chemical Composition Of Ground Black And Uncaria Fingerprint Study

Posted on:2004-07-14Degree:MasterType:Thesis
Country:ChinaCandidate:Y G YinFull Text:PDF
GTID:2204360092997338Subject:Pharmacy
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Di Wu is the dry rhizome of Anemone fiaccida Fr.Schmidt. It is distributed in the south part of China and used as folk medicine for detoxication, to expel! wind-evil and remove wetness-evil.The first part of the dissertation surveyed the chemical researches on plants of Anemone and chemical structure, extraction, researches on triterpenoid saponins of Anemone plants.The second part (experiment part) of the dissertation included:studies on extraction, isolation and structure identification of triterpenoid saponins of Anemone fiaccida Fr.Schmid: One new triterpenoid saponin was isolated from the ethanol extractive, it is identified as3-O-[P-D-glucopyranosyl-(1-4)-a -l-rhamnopyranosyl]-0leanoiic acid-28-O-[P-D-glucopyranosyl-(1-6)-P-D-glucpyranosyl-a-L-rhamnopyranoside].Fingerprint graphy: Chromatographic fingerprint, as extended progress of conventional identification of Chinese herbal medication, is nowadays gradually applied to quality assessment of TCM preparations and at the same time it is under heat debate. It should be significant to define the integrity and fuzziness is the fundamental attributions of chromatographic fingerprint. As a comprehensive quantifiable identification method, the authenticity, quality consistency and stability of herbal medication can be monitored and evaluated effectively. Obviously defining an herba! specification of chromatographic fingerprints. Whichever method is chosen, demands the highly concern on its specificity, reproducibility and applicability. It is understood, only with precision and attention to detail on the implementation of GAP on herbal material cultivation, GMP on manufacture procedure and GLP on experimental laboratories may chromatographic fingerprints be developed successfully as criteria for analysis. As for methodology, criteria on chromatpgraphic experimental, fingerprint recognition,were Iess than 3%...
Keywords/Search Tags:Saponin, Structure, Identification, Fingerscript Graphy, @ Anemone flaccida Fr.Schmidt, Uncaria rhynchophylla
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