Eliminate Anti-tang On Observation And Discussion Of The Efficacy Of Immune Infertility Antibody Series

Objective: To observe the effect of Xiao Kang Decoction (XKD) on immune infertility antibody series and analyze and investigate its pharmacologic and therapeutic function. The formulation of XKD was directed by tutor's theory of distinguish symptom therapy and formula principle. It followed the law of distinguish symptom therapy, also combined the new achievements of modern pharmacology and based on long-time clinical experience. Its basic method was to promote the circulation of blood and remove the blood stasis, aspirin had the function of counter the coagulation of the platelet which was similar to that of XKD. We used XKD in the treatment group, aspirin in the contrast group in the test to observe their therapeutic effect on immune infertility and compare them to find out whether there is difference between them.Thus we can obtain the objective basis of applying XKD.Method: We divided 79 patients who accord to the selection criteria into treatment group and contrast group randomly, 41 cases of control group, 38 cases of control group. The treatment group took XKD orally, two times daily, 100ml in the morning & evening, the contrast group took aspirin 50mg in the evening. One course of medical treatment lasted 3 months. (Stop the treatment during menstrual period. Condom should be used during sexual intercourse.) We checked the immune infertility antibody in the blood serum before and after the treatment. The therapeutic effect index: clinical cure: reexamine the antibody which was previously positive or/and slight positive after one course, they all turn negative; effective: for the sample that had one or more than one positive and/or slight positive antibody, the positive one turn slight positive or the slight positive one turned negative after one course, no effect: there was no change to the antibody which was previously positive and/on slight positive after one course. All the data were counted with SPSS software and the two sample rates were compared by x2-test.Results: Compare all the therapeutic effect indexes between the two groups after the treatment. As for the treatment group, clinical cure rate was 36.59%, effective rate was 48. 78%, total effective rate was 85. 37%, while those of the contrast group respectively were 5.26%, 10. 53%andl5. 79%, there was significant difference between the two groups. P<0. 005.Conclusion: Proved by the test, as for the patients who had sign of blood stasis, XKD's effect was better than that of aspirin, whose effect was limited. It proved that XKD can remove the blood stasis, promote the regeneration, improve the micro-circulation and harmonize the Chong and Ren meridian to adjust the immune function of the body and recover the impaired immune balance, inhibit the occur of the antibody in the blood, promote the decline of its level. It also proved that XKD had definite effect on the immune infertility antibody. At the same time, the test provides reliable evidence for its clinical application in the future. It'sunprecedented in treating immune infertility with method of promoting the blood circulation and removing the blood stasis, so it's of great significance in the aspect of the new drugs in treating the immune infertility.