| The foundation that acupuncture and moxibustion cures the disease is to the choice of patient's Shu Xue , and the point of the different position of health has its relatively different functions , namely functions of the point all have it peculiar. The peculiar theory of this kind of point comes from " the Yellow Emperor′s Internal Classic ". If "Spirit Pivot·nine stitch 12 original " page have " disease of having of the five internal organs, as fetch 12 former; Disease of having of the five internal organs, should produce 12 original , and original all appear to some extent, description that know it is original perfectly well , see it and answer , and know the harm of the five internal organs ". The basic main point with peculiar point can be interpreted as different points and have reflection different from other points and adjust to the function or illness of some one or some viscera or the body Whole function. The peculiar theory of point is to instruct through the ages acupuncture and moxibustion is clinical it is most the most important theoretical foundation too basically. Say to a certain extent , the ones that have no point are peculiar , there is no acupuncture and moxibustion to study.On the acupuncture and moxibustion circle, remain fragmentary going on systematic about point function getting peculiar research at present, remain overallly and observe competence in the phenomenon or the effect, it is less likely to summarize its law , the discussion of its mechanism has just started, it still takes a large number of jobs in the future. So this experiment regards low blood pressure as the research object, choose neiguan of the Pericardium Meridian of Hand-Jueyin , zusanli of the Stomach Meridian of Foot-Yangming, shuigou of the Du Meridian representative of treating the low blood pressure of three pieces of clinic , go on to these mechanism of treating the low blood pressure of three points with the kidney plainly - the blood vessel is tense and plain - the aldehyde firm ketone system is the main viewpoint, the comparative research of such a lot of position as circulation heart brain kidney ,etc., expect that the difference of the effect start the position to find three points and step up , and each peculiar function target is clicked, offer the new thinking of research for peculiar theory of point, choose to offer the experiment basis with ill point in order to treat the low blood pressure clinically too.Subject this experiment choose vein pump into nitre general sodium simulation old mouse acute low blood pressure model while being low dose of continuously, adopt and radiate the immune method , it it observes to be electric needle the shuigou,neiguan,zusanli etc. position RAAS system not different , circulation of mouse and brain of heart not big , low blood pressure of state and The influence of relevant materials, turn off the different function targets of three cave link arises in the comparative analysis ditch , thus offer the theoretical foundation for peculiar theory of Shu cave .Main experimental result:1 electricity is directed against the influence of blood pressure valueElectric needle works 20 minutes ,and you will find zusanlizu contrast to group rise notably than blood pressure (P<0.05), imprison group and contrast group and can not change remarkably (P> 0.05 ) than blood pressure value inside.2 electricity is directed against RAAS system and influence of relevant materials in circulationThe electric needle was after 20 minutes, an impact on circulation RAAS: neiguan group kidney plain level of group than contrast group is it rise obviously to have inside (P<0.05); zusanli group blood vessel nervous plain II than contrast group is it rise obviously to have level of group (P<0.05); shuigou group, neiguan group and zusanli group three groups and contrast group skin plain level rise obviously in comparing (P<0.05).3 electricity is directed against the local organization RAAS system and influence of relevant materialsThe electric needle was after 20 minutes, an impact on some RAAS of heart: shuigou and zusanli groups blood vessel nervous plain II than contrast group is it rise obviously to have level of group (P<0.05); shuigou and zusanli groups than contrast group aldehyde firm ketone level is it rise obviously to have (P<0.05); shuigou group contrast group skin plain level reduce obviously in comparing (P<0.05); shuigou and zusanli groups contrast group skin plain level rise obviously in comparing (P<0.05).The electric needle was after 20 minutes, an impact on some RAAS of brain: Close the group inside and contrast the group to obviously rise more than the plain level of kidney; Ditch group and contrasting the group to compare the plain level of heart sodium to reduce (P<0.05 ) notably; shuigou group neiguan group and zusanli group three group and contrast group skin plain level rise notably in comparing (P<0.05).The electric needle was after 20 minutes, an impact on some RAAS of kidney: Do not have remarkable influence on some RAAS of kidney to neddle neiguan ,zusanli and shuigou.Conclusion:1 viscera blood vessel expanding low blood pressure caused to the general sodium of nitre ,"shuigou"and"zusanli"have obvious function of increasing the blood pressure ,but electric needle"neiguan"has no effect on it . It is the ill daily cave as treating the low blood pressure inside on clinic, but the clinical manifestation of having the low blood pressure is extremely complicated, acupuncture and moxibustion treats this disease to all choose different points and make up the acupuncture and moxibustion prescription to treat to various kinds of symptoms too. Neiguan is regarded as the classical point in the acupuncture and moxibustion prescription of the low blood pressure , have peculiar targets to the heart to function , but probably just give birth to its target function of treating under the pathology state lying in heart oneself, and copies of experiment big low blood pressure of mouse state whether capacity blood vessel is it cause periphery blood vessel obstruction is it cause to drop to increase, unless and myocardium for contractile force the normal still, this point perhaps among not should testing,acupuncture "neiguan "one of reason where cave does not play a role in stepping up .2 The results of experiments are pointed out: Different points step up the effect is peculiar and the kidney in circulation is plain - the blood vessel is tense and plain - the aldehyde firm ketone system one is not the linear correlation, consult the experimental result resembled etc.: Causing the viscera blood vessel expanding low blood pressure with the general sodium of nitre, it mainly reduce the flow of kidney blood and step up to step up after the electric needle, we think to step up effect to be getting peculiar might to relevant with different different target of point different point, namely it getting peculiar, may more to act on kidney in local organization plain - blood vessel nervous and plain - aldehyde firm ketone system, but not RAAS while circulating . RAAS system of the shuigou some to the heart has peculiar targets to function : RAAS system of shuigou some to the brain has not been obviously influenced , but the plain level of heart sodium is reduced (P<0.05) notably, interior skin plain level rise notably (0.05 P<), brief on shuigou to step up centre mechanism of effect might have remarkable dependence with RAAS system , centre of position, and and interior skin plain rising of level closely linked with heart sodium plain reducing, but its concrete mechanism of stepping up still needs further further investigation. Zusanli have a peculiar target to heart some RAAS system to function too; zhsanli group have obvious regulating action either to brain some RAAS system , obviously influence to brain some heart sodium plain competence either, rise brain some interior skin plain level notably just , brief zusanli rising effect weaker than shuigou group in blood pressure, the plain level of heart sodium that can't cause the heart to be some with zhsanli of electric needle and then weaken heart some RAAS regulating function in blood pressure, short stepping up function have something to do plain in resisting partly too.Synthesize and state,shuigou ,zusanli and neiguan while treating the acute low blood pressure that the general sodium of nitre causes inside, really having different effects of increasing blood pressure . target organs of its function are different, the link of starting of function has difference too, these have offered certain experiment basis for the fact that Shuxue function is peculiar . |
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