The Chemical Constituents Of Notoginseng

Panax notoginseng(Burk.)F.H.Chen was a native perennial herbal plant belongin g to the Araliaceae family,whose another name was "San Qi" or "Tian Qi". In order to find more and more active agents from this plant,by means of the macro porous resin,repeated column chromatography,ODS and so on,nineteen compounds were isolated from the 70%EtOH extracts of the Panax notoginseng,and their structures were characterized on the basis of spectroscopic analysis and chemical evidence. They were identified as 3β,6α,12β,20(S)-20,25-epoxy-3,12-dih-ydroxy-dammarane-6-O-β-D-glucopyranoside (1),3β,6α,12β,20(R)-tetrahydroxy-25-meth-oxy-dammarane-6-O-β-D-gl ucopyranoside(2),3β,6α,12β,20(R)-tetrahydroxy-25-pentol-da-mmarane-6-O-β-D-glucopyr anoside(3),20(R)-ginsenoside Rhl(4),3β,6α,12β,20(S)-tetr-ahydroxy-25-hydroperoxy-23 -ene-dammarane-6-O-β-D-glucopyranoside(5),notoginsenoside R₂(6),ginsenoside Rg₁ (7),ginsenoside Rd(8),ginsenoside Rb₁(9),notoginsenoside k(10),ginsenoside Rb₃ (11),notoginsenoside R₁(12),ginsenoside Rh₄(13),ginsenoside Rk₃(14),20(R)-gins enoside Rg₃(15),ginsenoside Re(16),notoginsenoside R₆(17),notoginsenoside R₃ (18),daucosterol(19).Among them,compound 2,5 were two new compounds,1 was an novel natural product.