Anti-inflammatory The Guben Zhikepingchuan Granule In Treating Asthma, Immune Experimental Research

Purpose:In fact I cough heavily on the particles are based on optimum combination for clinical treatment of asthma made effective prescriptions, cough and foundation of bronchial asthma (virtual particles indications of cough, asthma wheezing) promoting, bosom frowsty, larynx, shortness of breath, fatigue, sweating, curative effect in clinical applications. This topic in TCM theory as the guide, cough and foundation through the anti-inflammatory experiments and particle immune experiment, evaluation and explore consoliated cost cough heavily in treating bronchial asthma with particle mechanism for clinical use and development, and provide basis for new drugs.Material and method:First, four experiments of mice and rats required in accordance with the requirements of experiments are divided into six groups, in fact, control and cough particle high, medium and low dose group GuiLong, cough and asthma ning capsule group and dexamethasone chips group. In fact cough heavily were observed for acute inflammation and the effect of chronic inflammation, And humoral immune cells from the two aspects of observation and immune to cough heavily particles in fact immunosuppression.Results:In fact cough heavily particles may inhibit xylene-induced ear acute inflammatory swelling, Restrain rats AGAR granulation swollen chronic, Increases in serum hemolysin antibody cargoes, Weakened 2,4-diflooronitrohenzene nitro chlorobenzene mice late-onset hypersensitiity reactions. Obviously against acute inflammation and chronic inflammation, humoral immune cells and immune suppression.Conclusion:The research results show that the foundation cough heavily particle has obvious anti-inflammation and immune suppression effect of treatment of asthma, and has good effect. For the preparation of clinical medicine and further development provides a new pharmacology.