| Objective:Lipoprotein (a) [LP (a)] in type 2 diabetes and non-phlegm phlegm in the distribution and in chronic vascular complications of type 2 diabetes, the distribution of the study Lp (a) and related the relationship between indicators to explore type 2 diabetes and the pathogenesis of chronic vascular complications, type 2 diabetes, so as to the objective of TCM to provide reference.Methods:81 patients with type 2 diabetes,46 cases were male and 35 female, aged 28-78 years of age, duration of 6 months-35 years. Reference to 1993, the Chinese Society of Traditional Chinese Medicine Diabetes (diabetes) Professional Committee to develop a "Diabetes (diabetes) TCM syndrome and efficacy assessment phases reference standard" in the (attached) dialectical Diabetes phlegm diagnostic reference standard in the diagnosis, including 42 cases of phlegm, phlegm 39 cases of non-clinical or chronic complications of vascular complications,55 patients without chronic vascular complications or complications were 26 cases, and collected medical history inquiry and palpation by way, try to check the following day to collect the clinical syndrome testing indicators:Lipoprotein (a), body mass index (BMI), waist circumference, fasting plasma glucose (FPG), glycosylated hemoglobin (HbAlc) and lipid-related indicators (TC, TG, HDL-C, LDL-C).Results:Type 1.2 Diabetes LP (a) level was significantly higher than the control group (P<0.01), in which phlegm type 2 diabetes patients LP. (a) level higher than phlegm group, the difference was statistically significant (P= 0.045<0.05), phlegm group than non-healthy control group no significant difference (P> 0.05); 2. diabetic vascular disease group LP (a) levels were significantly higher than that of non-vascular disease, significant difference (P= 0.000< 0.01), non-vessel disease group LP (a) than the healthy control group no significant difference (P> 0.05); 3.2 diabetes blood LP (a) level and age, disease duration, waist circumference, FPG, HbAIc, BMI, TC, TG, LDL-C and HDL-C had no correlation (P all> 0.05); 4.2 diabetic patients compared with healthy controls of the syndrome groups TC, TG, LDL-C higher, HDL-C levels lower, the difference was significant (P all<0.05), and the syndrome of type 2 diabetes, lipid composition between the groups (TG, LDL-C and HDL-C) significantly different (P all<0.01);2 chronic vascular complications of diabetes group than in non-vascular disease significantly increased phlegm syndrome group, significant difference (P<0.01). Conclusion:Patients with Type 1.2 LP (α) was significantly higher than the healthy control group, in which phlegm Group LP (α) level higher than phlegm group, non-phlegm syndrome group and healthy control group, no difference, suggesting that LP (α) can be used as type 2 diabetes, the pathological substance of phlegm.2.2 diabetic vascular disease LP (a) level was significantly higher than that of non-vascular disease, non-vessel disease group LP (a) was no different than the healthy control group, suggesting that LP (a) of type 2 diabetes as a risk factor for vascular complications, can detect, assess the chronic vascular complications of type 2 diabetes.3.LP (a) with age, disease duration, HbAIc, waist circumference, FPG, BMI, TC, TG, LDL-C and HDL-C had no correlation, suggesting that LP (a) independent of lipid metabolism in type 2 diabetes, independent metabolic pathways. 4.2 diabetic patients with chronic vascular complications of phlegm phlegm was significantly higher than non-group, suggesting that type 2 diabetes may be phlegm type 2 diabetes and disease pathology of chronic vascular disease, diabetes and chronic vascular complications of chronic can be used as the basic rule is one of the phlegm. |
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