| Objective: Currently, dementia has become the primary cause ofdisability over60years old, and the current epidemiological data on dementiaprevalence and risk factors of age groups is less.The retired veteran cadres has a perfect health system, and theepidemiology investigation work is easy to organize and implement,the crowdis good stability, it can be not only ensure that epidemiology investigationwork completed high quality, but also can get more reliable data.The study that based on the elderly population of the troops retired cadresis for the prevalence of dementia and risk factor, in order to evaluate theprevalence of dementia and obtain the risk factors of dementia.So we canexplore the possibility of early intervention programsMethods：1Stratified cluster sampling was used to conduct an epidemiologicalstudy of the80-year-old and over80-year-old retired army veteran in15Beijing retired cadres from December2009to July2011.2All investigators in the research were physicians or graduations.All ofus have had training on the system survey methods before starting the researchprogram.We made consistency test on the cognitive scale score,and thequanlity control was made by the special man.3The two stages survey methods, according to the army retired cadresnervous system health sampling questionnaire was used to investigate therespondents and the insiders face to face in their home or the clinic.The firststage is recording the population sociology material,previous medical history,drinking and smoking history of the respondets,using the simple intelligentstate examination (MMSE) scale and Montreal cognitive scale (MOCA), dailyliving skills (ADL) scale and depression self rating scale (CES-D) screening to screen.The cases whose score higer than the devided point were the men withnormal congnitive function,and the cases whose score lower than the devidedscore were sent to the second stage to have the congnitive assessment by themore detail scale.The people who had the normal congnitive function were asthe control group,the dementia were as the case group.The unmatchcase-control study was made on the two groups4Using Epidata3.0application software to create a database, all datawas entered with line double entry form and had consistency examination.Using the SPSS13.0to make the statistical analysis. Single factor analysis wasused firstly, the differences were statistically sigmificant when P <0.05.Thenthe unconditional Logistic regression analysis was made, in which thedementia as the dependent variables and the statistically significant variablesas the independent variables. Use OR and P value to evaluat the associationand the independence between the risk factors and the dementia.5The main outcome measures were the crude prevalence of dementiaand its main subtypes, and the crude prevalence of all ages.The OR values andP values of the various possible dementia risk factors.Results：1597veteran cadres had joined in the survey, the response rate was90.5%,569were men and28were women.Their age were from80to98,whose mean age were83years old.247people had the normal cognitivefunction and113people were dementia.2Distribution of dementia type:71were AD,31were VD,11were othertypes of dementia. The total prevalence rate of dementia was18.9%, and theprevalence rate of AD, VD, other types of demetia was11.9%,5.2%,1.8%separately.3Dementia risk factors:(1) Population and social factors: Univariateanalysis showed that the OR of the dementia and the control groups stratifiedby age,80to84years,85to89years, over90was3.32(95%CI2.19,5.04), P<0.01,the differences of age between the two groups were significant.Whenthey were stratified by years of education, under6years,6to12years, more than12years,the OR was2.07(95%CI1.44,2.97), P <0.01,the differences ofthe years of education were statistically significant. The differences were notstatistically significant when the two groups were stratified by gender, P>0.05.(2) Vascular risk factors: The univariate analysis results showed that:compared with the cognitive function in normal, OR of the people withdiabetes was2.37(95%CI1.49,3.77), P <0.01; OR of the people with historyof hypertension was2.40(95%CI1.44,4.00), P <0.01; OR of the people withstroke history was3.20(95%CI1.93,5.31), P <0.01; the proportion of thehyperlipidemia, coronary heart disease, irregulardisorders in the dementiagroup was slightly higher than non-dementia group, but P>0.05, thedifference was not statistically significant.(3) Other possible risk factors: therates of smoking, drinking, mental trauma and electromagnetic exposure in thedementiawere all higher than those in the control group, but this was notstatistically significant.4Vararious factor analysis: unconditional logistic regression model werechosen.The results showed that age, stroke, diabetes, high blood pressure andthe shorter years of education were the independent risk factors of dementia,the OR value and95%confidence interval were2.87(1.83,4.50),2.41(1.37,4.23),2.05(1.23,3.44),1.80(1.02,3.15) and1.86(1.26,2.75) separately.Conclusion:1Elderly population with a higher prevalence of dementia,and theprevalence increasing by age, the rate of AD is higher than VD.2The age, low education of year, hypertension, diabetes, and stroke forolder population are independent risk factors of dementia.3Smoking, Alcohol intake, mental trauma history, electromagnetic fieldexposure, hyperlipemia, coronary heart disease, and arrhythmia whether arerisk factors of dementia for the senior citizens group or not are still need to bestudied further.4There will be great significance to reduce the incidence of dementia forprevention of high blood pressure, diabetes, stroke and improve educationlevels... |
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