| Objective:Through clinical observation, the discussion stomach medicine I Decoction in treatment of chronic atrophic gastritis with spleen deficiency blood stasis syndrome clinical curative effect and mechanism of.Clinical data:Huazhong university of science and technology, affiliated tongji hospital jingzhou in March2010-June2011regions expert outpatient service by gastroscope and pathology diagnosis of chronic atrophic gastritis patients, syndrome differentiation of spleen deficiency, blood stasis syndrome, a total of66patients for clinical observation.Methods1. With chronic atrophic gastritis criteria for the diagnosis of66cases of patients, according to the order of lto lwere randomly divided into treatment group and control group with33cases in each group. Two groups of CAG patients with clinical data to compare difference not to have statistical significance (P>0.05), comparable to. The treatment group were treated with gastric drug I medicine side200ml,3times a day orally; the control group was given commonly used medicines Weifuchun pian in treating,4at a time,3times a day. Two cases with a course of3months, observation of treatment1. During the medication to deactivate the other in treatment of chronic atrophic gastritis with integrated traditional Chinese and Western medicine. Fasting spicy food, raw chilled products, light diet. Project:observation were observed before and after treatment in two groups of clinical symptoms, gastroscopic and histopathologic examination performance, syndrome efficacy, and by statistical analysis. After the end of the treatment, follow-up of6months, the long-term curative effect observation.2.Statistical analysis methods:SPSS17.Ostatistical software for data analysis. Rank data by using the Ridit analysis, measurement data using t test, count data by using x2test.Results:1. In two groups of patients with traditional Chinese medicine mainly clinical:with patients more often appear clinical symptoms according to cure, effect, effective, ineffective investigation, results show the total effective rate in the treatment group was significantly higher than that of control group (P<0.05);2. Two groups of patients under gastroscopy and pathological comparison of efficacy, statistical analysis, two groups of patients had significant difference (P<0.05), the tips of the two group of drugs in the treatment of CAG is effective; the two group patients after endoscopic and pathological efficacy comparison: the total effective rate in the treatment group was significantly higher than that of the control group;3. Two groups of patients after treatment of HP infection to improve the situation, the treatment group than in control group with significant difference (P<0.01);4.Two group patients after comprehensive comparison of efficacy: in treatment group, the cure rate is9.09%, the markedly effective rate was36.36%, the total efficiency of81..82%; the control group the cure rate was3.03%, markedly effective rate was18.18%, the total efficiency of57.58%. Integrated effect of the two groups were compared with statistical significance (P<0.01), the treatment group was superior to control group comprehensive effect.5. After the end of the treatment, follow-up of6months, the treatment group the recurrence rate was24.24%, compared to the control group for a recurrence rate of45.45%, two group of recurrence rate had a significant difference (P<0.05), the observation group was better than the control group in long term efficacy.Conclusion:Stomach medicine I Decoction CAG Deficiency Blood Stasis Decoction in treatment of patients with clinical symptoms and signs, therapeutic effect of gastroscope pathological efficacy, efficacy, efficacy, and commonly used in Chinese medicine by pills group compared to stomach, efficacy has obvious advantages, and in the medication process not found on the heart, brain, liver, kidney and other important organs with obvious side effect, worthy of further clinical study. |
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