The Clinical Efficacy Of Boxintong Capsule In Treating Ischemic Stroke

Objective:Observ the Michiharu medicine Boxintong capsule in treating ischemic stroke clinical efficacy, and to provide new ideas for prevention and treatment of clinical ischemic stroke.Methods:Select the120cases included in the standard treatment compliance of Neurology, First Hospital, Wuhan City in June2011March2012patients (male70, female50cases), divided into an observation group and control group randomly selected through a computer. Control group given conventional anti-platelet aggregation, improve blood circulation, nutrition, brain cells to treat, and adjusting them according to the condition of the patient blood sugar, regulate blood pressure and adjust blood lipids and reduce intracranial pressure, prevention of stress ulcer prophylaxis against infection, to maintain water and electrolyte symptomatic and supportive treatment of balance; observation group in addition to the treatment given above, and the other to give Boxintong capsules of50mg/3times a day oral administration. Reference to the stroke patients with neurological deficit scores Standard, adopted by the Fourth National Cerebrovascular Disease Conference in1995, and clinical efficacy were assessed by the reduction of neurological deficit integral value and the improvement of the state of the patients living skills. TCM symptom score and the score of activities of daily living status of patients before and after treatment, and clinical efficacy. Also measured before and after treatment the patient’s blood rheology, platelet aggregation capacity, as well as on blood and urine monitoring will be routine, liver, kidney function, blood pressure, electrocardiogram, blood clotting function, observed during the treatment of patients with adverse reactions, to assess the safety of the drug.Results:Give the medication after45days, the efficacy of TCM symptoms and clinical efficacy assessment showed observation group (Boxintong capsules treatment group) was significantly better than the control group (p<0.05). Activities of daily living status, TCM symptom score compared with the efficacy of the observation group than the control group (p<0.05). The neurological deficit scores: two groups with the group before treatment, after treatment were significantly better than before treatment (p<0.05). Blood rheology and platelet aggregation ability:observation group and control group hemorheo logical parameters have different degrees of recovery after treatment; the two groups in the observation group than the control group to observe the impact of group platelet function than the control group (P<0.05). Security observed only in control group1cases of abnormal liver function, I patients had no abnormal changes.Conclusion:The results show that the clinical efficacy of the yang of Chinese medicine Boxintong capsule treatment of ischemic stroke is significantly better than the control group, but no serious side effects. More effective in promoting the recovery of neurological function and improve clinical symptoms and improve daily living skills. Right the hemorheology the recovery, the improvement of platelet function than the control group significantly. But the main defect of this experiment is the small sample size, selected patients mainly in Wuhan, a clear conclusion has yet to be confirmed by the large sample large-scale randomized trials.