Influence Of Stress From The Combination Of Molybdenum And Cadmium On The Content Of Trace Elements In Goat Digestive System

This experiment was conducted to determine the influence of stress from the combinationof molybdenum and cadmium on the content of trace elements in goat digestive system.63goats were selected and divided into seven groups randomly. The ammoniummolybdate[（NH4）6Mo7O24·4H2O] and cadmium chloride （CdCl2） were used as sources ofmolybdenum and cadmium in this experiment. Goats which were drenched a certainamount（equal to the dose level of molybdenum and cadmium administered in each treatedgroup） of deionized water were used as the control group. The experimental goats wereadministered orally different dose levels of molybdenum and cadmium, and they weredivided into6groups: low-dose cadmium combined with low-dose molybdenum group(15mg Mo·kg^-1·BW+0.5mg Cd·kg^-1·BW), low-dose cadmium combined withmoderate-dose molybdenum group (30mg Mo·kg^-1·BW+0.5mg Cd·kg^-1·BW), low-dosecadmium combined with high-dose molybdenum group (45mg Mo·kg^-1·BW+0.5mgCd·kg^-1·BW), high-dose cadmium combined with low-dose molybdenum group (15mgMo·kg^-1·BW+1mg Cd·kg^-1·BW), high-dose cadmium combined with moderate-dosemolybdenum group (30mg Mo·kg^-1·BW+1mg Cd·kg^-1·BW), high-dose cadmium combinedwith low-dose molybdenum (45mg Mo·kg^-1·BW+1mg Cd·kg^-1·BW). The experimentalperiod was50days, and digestive tracts were obtained on0days,25days and50days bykilling3goats from each group respectively. Subsequently, their content of Mo, Cd and Cuwere measured. The results were as follows:（1） As time went on, the content of Mo and Cd in the digestive system of the poisonedgroups’ goats were generally increased significantly generally when compared with thecontrol group （P<0.05）. On25days and50days, with the increase of concentrations ofmolybdenum and cadmium, the content of Mo and Cd in the digestive system of thepoisoned groups’ goats were generally generally increased significantly in comparison withthe control group （P<0.05）.（2） As time went on, the content of Cu in the rumen, abomasum, duodenum, ileum, cecumof the poisoned groups’ goats were generally decreased significantly generally whencompared with the control group （P<0.05）. On25days and50days, with the increase ofconcentrations of molybdenum and cadmium, the content of Cu in the abomasum,duodenum, ileum, cecum, colon of the poisoned groups’ goats were generally decreasedsignificantly generally when compared with the control group （P<0.05）.（3） On25days, with the increase of concentrations of molybdenum, the content of Cu inthe rumen fluid and feces of the low-dose cadmium groups’ goats were generally increasedsignificantly generally when compared with the control group （P<0.05）. On50days, withthe increase of concentrations of molybdenum, the content of Cu in the rumen fluid andfeces of the high-dose cadmium groups’ goats were increased significantly generally when compared with the control group （P<0.05）.The results showed that molybdenum and cadmium could be accumulated in goatsdigestive tract, and they had a synergetic effect. Furthermore, molybdenum and cadmiumhad an antagonistic effect together on gastrointestinal tract’s absorption and accumulationof Cu as well as promoted the excretion of Cu. This experiment provided a referencefor the treatment of molybdenum and cadmium toxicosis.