Investigation Of Glycosylated Hemoglobin A1c Control And Its Influence Factors In Type2Diabetic Patients

Objective1.To investigate outpatients of diabetes，evaluate glycosylated hemoglobin A1c (HbA1c) control and its influencing factors in type2diabetic mellitus (T2DM) patients.2.Compliance management of diabetes in clinical work and analyze the association of HbA1c control with diabetic complications, and explore how to do clinical work in order to improve the overall level of control of diabetic patients.Methods Since April2012to June2012in the General Hospital of Ningxia Medical endocrinology specialty clinic in patients with type2diabetes, a total of400cases.The survey is divided into five parts:(1) general information;(2) self‐monitoring;(3) the course and hypoglycemic treatment programs;(4) complications, complications and duration of disease;(5) a fasting blood glucose (FBG),2‐hour postprandial blood sugar (2hPBG), HbA1c etc.other results. The above data were grouped according to different standards and application SPSS17.0statistical analysis.Results1. HbA1c compliance rate of21.75%, the compliance group did not meet the group in the information age, duration and lipid control situations baseline comparison, the difference was not statistically significant.2. The survey includes229cases of male and female171cases. The age of onset was48±11.0years for male,51±10.2years for female. The incidence of female later than male, the difference was statistically significant (P=0.032).3. With the duration of the extension, the compliance rate of patients with HbA1c downward trend, and the course of the disease in patients less than5years glycated hemoglobin standard higher than that in the course of the disease is longer than five years, the difference was statistically significant (P <0.05).4. In400patients, of FBG,2hPBG, TG, TC, LDL‐C, BP, BMI lower proportion of unsatisfactory control were16.75%,7.25%,44.75%,44.25%,42.25%,36.75%,42.25%.5. The number of self‐monitoring and ot for self‐testing is199and201.HbA1c values were8.63±1.89,8.80±1.78, the difference was not statistically significant (P=0.345).6. The study showed a high prevalence of complications in patients with T2DM, diabetic neuropathy (DNP) prevalence rate of32%, diabetic kidney lesions (DN)31.25%, diabetic retinopathy lesions (DR) of26.5%, diabetic foot (DF) is6%. HbA1c did not meet the group complications prevalence is slightly higher than in the standard group, but the difference was not statistically significant (P>0.05).7. No significant difference between different treatment options, patients HbA1c value etc., but in the course of the disease there is a statistically significant difference (P <0.01)8. Insulin group was significantly higher than the incidence of complications (retinopathy, peripheral neuropathy, kidney disease) is not applied, the insulin group, and there is a statistically significant difference (P <0.01).Conclusion:1. The study showed the HbA1c compliance of T2DM is low; complications between HbA1c and course of the disease, treatment options, self‐management, there is a correlation.2. T2DM patients lack the necessary medical education, self‐management is not standardized or even lack.3. The course of the disease is the main influencing factors of treatment options, and lack of scientific.The study suggests that clinicians should be according to the course of the disease and the individual characteristics of the patients, the appropriate choice of treatment options, and focus on improving patient self‐management awareness.