| Objective: This subject clinical trials, observed hoPane Gui souP treatment ofresPiratory infections the cold table imaginary and stagnant heat of the clinicalefficacy, safety, and exPlore its theraPeutic mechanism.Design method: Press the cases included in the standard selection of resPiratory tractinfection (cold table imaginary Chief Yu-heat syndrome)72Patients, randomizedcontrolled observed treatment grouP and a control grouP of36cases each. The controlgrouP select cold heat Particles treatment; treatment grouP treatment with Chinesemedicine hoPane Gui souP. Course of three days. Observation of clinical symPtomsand liver and kidney function, blood count, chest X-ray observations of laboratorytests before and after treatment, and3days later a second blood, liver and kidneyfunction, and chest X-ray to make efficacy evaluation.Results:(1) Basic information: two grouPs of Patients in the comParison of basicinformation such as gender, age, duration of disease, Chinese medicine symPtomscore, body temPerature, the statistical results were not statistically significant (P>0.05); therefore can be considered as two grouPs of Patients withbefore the basicinformation is no difference between comParable.(2) TCM symPtoms Points: aftertreatment, the treatment grouP and the control grouP can be significantly imProved,fever, chills, sPontaneous PersPiration, uPset, nasal congestion, runny nose, bodyaches, cough symPtom scores (P <0.01); treatment grouP stuffy, runny nose, coughthree symPtom score imProvement than the control grouP (P <0.05).(3), symPtomtotal score: total Points in the two grouPs of Patients before and after treatment grouPcomParisons, the results were statistically significant (P <0.01); comPared the two grouPs after treatment between the two grouPs, the results are statistically significant(P <0.05), indicating significant imProvement in Patients’ symPtoms after treatment,the two grouPs than those before treatment, and the imProvement of the treatmentgrouP than the control grouP.(4), body temPerature: two grouPs of Patients beforeand after treatment the temPerature within the grouP comPared with the treatmentgrouP and the control grouP could significantly reduce the Patient’s temPerature (P<0.01); temPerature of the treatment grouP and the control grouP were comParedbetween grouPs, no statistical difference significance (P>0.05).(5) disease efficacy:After three days of treatment, the two grouPs total cure efficiency and total efficiencyof the treatment grouP was14.7%and94.12%,6.5%and74.2%in the control grouP.ComParison between the efficacy of grouP, the results were statistically significant (P<0.05). The treatment grouP was significantly better than the control grouP.(6), safetyindicators: blood count and kidney function in two grouPs of Patients before and aftertreatment showed no abnormality; t-test showed that, after three days treatment grouPcomPared before and after treatment the Patients blood count, liver and kidneyfunction, WBC, NEUT%decline, the difference was statistically significant (P <0.01),but were within the normal range; each of the other safety indicators before and aftertreatment were within the normal range, the difference was not statistically significant(P>0.05).Conclusion: the hoPane Gui souP and cold-disPelling relieving, heat Chufan, the roleof the uPPer resPiratory tract infection Syndrome is the cold table imaginary andstagnant heat of the main, can significantly imProve their cold symPtoms, side effects. |