Studies On The Chemical Constituents Of Chaenomeles Speciosa

Chaenomeles speciosa (Sweet.) Nakai belongs to Chaenomeles of Rosaceae. It is adeciduous tree or shrub exclusively belonging to China. It has been cultivated from easternprovinces such as Liaoning, Shandong, Zhejiang to western provinces such as Xinjiang,Tibet, from southern provinces like Yunnan, Guizhou to northern provinces like Gansu,Hebei.Chaenomeles speciosa has another popular name called ‘fruit with one hundred bene-fits’. It is an edible plant with important ornamental uses, listed as one of the first batch ofmedicinal and edible food by Ministry of Health in2003. It has been used as a medicinefor a long time and mainly been utilized as a cure for lumbar and leg pain, rheumatoid art-hritis, viral hepatitis and other diseases. At the same time, as an edible fruit, it has been ap-plied to fields such as cosmetics and health products.The subject of this paper, the Chaenomeles speciosa, is not only the authentic speciesfrom Chinese Pharmacopoeia(2010), but also the one being produced from Changyang,Hubei Tujia Autonomous Region, which is one of the earliest Chaenomeles speciosaplanting GAP base. We used the systematic solvent extraction method and modernseparation technology,such as normal and reversed phase silica gel,macroporous resin,Sephadex LH20, MCI-GEL column chromatography and preparation of high performanceliquid chromatography to isolate and identify the chemical components.40compoundshave been isolated. According to the physical and chemical properties and spectral datarelated to the structural analysis,26compounds have been identified which include16phenolic compounds,2steroids,2terpenoids,6flavonoids. Among them,2new compou-nds have not yet been.11were the first time been isolated from the genus.The26compounds were identified as:(1)4-hydroxy-benzoic acid(2)3,4-dihydroxy-benzoic acid(3)3,4-dihydroxy-benzoic acid n-butyl ester(4)p-coumaric acid (5)caffeic acid(6)caffeic acid n-butyl ester(7)1-O-[(E)-p-cumaroyl]-β-D-glucopyranose(8)1-O-[(E)-caffeoyl]-β-D-glucopyranose(9)3-O-(E)-p-coumaroyl quinic acid(10)3-O-(E)-p-coumaroyl quinic acid n-butyl ester(11)3-O-(E)-caffeoyl quinic acid n-butyl ester(12)5-O-(E)-[(3,4-methylenedioxy)-cinnamoyl]quinic acid methyl ester(13)3-O-(E)-caffeoyl quinic acid(14)1-O-(E)-caffeoyl-3-O-(Z)-p-coumaroyl quinic acid n-butyl ester(New)(15)1-O-(E)-caffeoyl-5-O-(Z)-caffeoyl quinic acid n-butyl ester(New)(16)3-hydroxybutanedioic acid methyl ester(17)β-sitosterol(18)daucosterol(19)oleanolic acid(20)masilinic acid(21)quercetin(22)catechin(23)epicatechin(24)catechin-(7,8-bc)-4β-(3,4-dihydroxyphenyl)-dihydro-2-(3H)-pyranone(25)catechin-(7,8-bc)-4α-(3,4-dihydroxyphenyl)-dihydro-2-(3H)-pyranone(26)cinchonain I c(d)...