Application Of Nano-carbon In Lymph Node Dissection For Thyroid Cancer And Protection Of Parathyroid Glands

Objective: To explore the new method to identify and protect parathyroid glands inneck lymph node dissection for patients with thyroid cancer.Methods:100patients with thyroid cancer who were treated from April2012toOctober2013were selected. All the patients were given total thyroidectomycombined with central neck lymph node dissection by the same surgeon. During theoperation,50patients who used nano-carbon suspension were included in experimentgroup, and50patients who did not use nano-carbon suspension were included incontrol group. Changes of parathyroid hormone before surgery and at72h aftersurgery between two groups and of serum Ca2+level within72h after surgery, as wellas postoperative parathyroid pathological and lymph node dissection results, werecompared.Results:8and1parathyroid glands were detected pathologically in control andexperimental group, respectively. Decrease of parathyroid hormone at48h occurred in7patients of the control group and1patient of the experimental group. Hypocalcemiawas found at48h after surgery in10patients of the control group and2patients ofthe experimental group. There was a statistical difference between two groups. Thepatients of the control group and were followed up for3months, and2patients withhypocalcemia were found; and those of the experimental group were followed up for3months, and no case with hypocalcemia was observed. A total of135and116lymphnodes were dissected in the experimental group and control group (hereinafter, thesame order), among them, metastases of118and68lymph nodes were found, withthe positive rate of87.4%and58.6%in the two groups.Conclusions: Nano-carbon suspension can cause a development of the thyroid glandand the central lymph node and a negative development of parathyroid glands.Careful identification and removal of black-stained lymphatic tissues in the process oftotal thyroidectomy with neck lymph node dissection can not only ensure a completelymph node dissection, but also prevent parathyroid damage, thus effectively reducingthe incidence of hypoparathyroidism.