Analysis Of Central Lymph Nodes Metastatic Risk Factors In Hashimoto’s Thyroiditis Coexisting With Papillary Thyroid Carcinoma

Objective：Hashimoto’s thyroiditis and papillary thyroid carcinoma have a closerelationship. We analyzed clinical data of patients with chronic lymphocyticthyroiditis, to discover the characteristics of both the pathology. Currently, there is noclear surgical choice of papillary thyroid carcinoma associated with chroniclymphocytic thyroiditis surgical choice. So an analysis of papillary thyroid carcinomaassociated with chronic lymphocytic thyroiditis pathology can provide a guide forclinical treatment.Methods: The study subjects were697patients all treated at the Department ofThyroid Surgery,1st Hospital of the Jilin University, Changchun, China from2012.09to2013.09. Inclusion criteria: the information of the patients is complete and thepostoperative paraffin pathological diagnosis is thyroid papillary carcinoma.Intraoperative frozen pathological guides the operation. In697patients, there are192cases of patients associated with chronic lymphocytic thyroiditis. We analyze thepathological difference between papillary carcinoma patients and associated withchronic lymphocytic thyroiditis patients, and also the risk factors on lymph nodemetastasis of PTC patients combined with HT.Result：There are697PTC patients, including192cases with HT. When the PTCis associated HT, the lymph node metastasis rate decreases. At the same time, whenthe patients with HT, the tumor diameter is smaller. For PTC with HT, age, diameterof tumor, extrathyroidal extension, multifocal and central lymph node metastasis aresignificantly correlated at the0.05level. There is no significant correlation betweengender and the metastatic rate of the lymph node. When younger than45years old,tumor diameter less than1cm, no extrathyroidal extension, the central region lymphnode metastasis rate decreases.Conclusion：1. Thyroid papillary carcinoma with Hashimoto’s thyroiditis, tumor is smaller.2. For thyroid papillary carcinoma with Hashimoto’s thyroiditis, the lymphnode metastasis rate is low.3. Age <45years, tumor diameter≥1cm,extrathyroidal extension, are the risk factors on central lymph node metastasis ofthyroid papillary carcinoma with Hashimoto’s thyroiditis.