Shanxi Between Clinical Epidemiology Of Gastrointestinal Stromal Tumors

Objective To explore the clinical epidemiological characteristics of gastrointestinal stromal tumor (GIST) of shanxi province.Methods Screening method to collect in Shanxi Province, from January1,2008to2011december31diagnosed cases of gastrointestinal stromal tumors. All cases of diagnosis of GIST were cut white film by the Shanxi Tumor Hospital Pathology unified analysis of diagnostic data obtained analysis by spss softwareResults A total of518cases of GIST was found from January2008to December2011.2008found72cases,the incidence is2/1000000.2009found146cases,the incidence is4.1/1000000.2010found147cases,the incidence is4.1/1000000.2011found153cases,the incidence is4.3/1000000. According to census data calculation in2008China age standardized incidence2/a, the world age standardized incidence rate is1.45/a. In2009, the Chinese age standardized incidence rate of3.6per million, the world age standardized incidence rate is2.7/a. In2010, the Chinese age standardized incidence rate of3.5per million, the world age standardized incidence rate is2.7/a. In2011, the Chinese age standardized incidence rate of3.6per million, the world age standardized incidence rate is2.8/a.All of them belonged to the Han nationality. There was no statistical significance between the two sexes. The ages were between24to85years, and the median age was58years. The disease incidence increased along with the increase of age. Patients age mainly distributed in55-80year olds. More cases were found in Taiyuan96(19.8%), Changzhi78(16.1%) and Jinzhong63(13%) city, and most of them lived in the rural area. GIST may occur in any part of the digestive tract, and the predilection sites were stomach, small intestine, colon, rectum and esophagus.89.8%of them were in the gastrointestinal tract, the other10.2%were not. we called it EGIST.it rooted in mesenteric omental and retroperitoneal. As to the histological types,78.1%were spindle cell type,8.9%were epithelial cell type, and13%were mixed cell type. The tumor size mainly distributed in2-5cm141(33.3%) and6-10cm130(30.7%).Course of disease mostly in less than half a year.The commonest symptoms were abdominal pain.gastrointestinal bleeding. With a large number is asymptomatic or physical examination lumps. Nausea and Vomiting is rare.Conclusion Gastrointestinal stromal tumor is a scattered distribution of a disease, but also the low incidence of the disease. Shanxi Province, the incidence is lower than the United States and Europe. We have the incidence of statistics may be underestimated. Objective Recently, The progress of gastrointestinal stromal tumor and its research of the pathogenesis, makes the diagnostic standard revision, and promoted the development of molecular targeted therapy, the selection of treatment need to be more precise incidence of GIST, distribution, clinical features, prognostic factors of information.Methods Collect gastrointestinal stromal tumor cases and suspicious gastrointestinal stromal tumor cases of Shanxi Province on January1,2010to December31,2010, all cases were chipped white piece for shanxi provincial tumor hospital pathology department to analysis diagnosis, the data obtained analysised by SPSS statistical analysis software of description.Result The cases of GIST we found in2010is147cases, incidence of GIST is4.1/a. Each area at different rates, taiyuan highest6.0per million, luliang lowest2.4/a. In the gastrointestinal stromal tumor patients, there is no statistical significance between men and women. At age29-85years distribution, median age is56.8years, the incidence of GIST increases with age, and in the65-69years old peak, incidence is22.4/a. The cases of tumor in stomach is95cases (66.9%), small intestine22cases (15.5%), escherichia10cases (13.3%), esophageal2cases (1.4%), extra-gastrointestinal13cases (9.2%). Tumor size distribution:^2cm29patients (23.2%)(2,5]39cases31.2%.(5,10] and cases,30.4%and>10cm,19cases,15.2%. The shuttle type cell108cases (77.7%), epithelial type15cases (10.8%), hybrid16cases (11.5%).Conclusion GIST has not been fully aware of, its incidence, distribution, clinical invasive have been underestimated.