Single And Multiple Cold Crystalloid Myocardial Protection Immature Blood Perfusion In Clinical Research

Objective：Investigate the single and multiple perfusion of coldcrystalloid hyperkalemic blood cardioplegia on myocardial functionin immature。Method：random sampling60congenital heart disease infants intoa single cold crystalloid perfusion high potassium blood cardioplegiagroup (A) and conventional perfusion repeatedly the blood of coldcrystalloid cardioplegia group (B)(n=30). Jugular vein andcoronary blood collected at six point detection of atrial natriureticpeptide (ANP) and calcitonin gene-related titanium (CGRP),endothelin (RT-1) and troponin (cTn-T), cardiac enzymes. clipping asmall piece of right atrial organizations at the start and end ofsurgery, electron microscopy of myocardial ultrastructure structurechanges. The application of statistical analysis of experimentalresults to compare a single infusion high potassium cold crystalloidblood cardioplegia and the conventional perfusion repeatedly coldcrystalloid hyperkalemic blood cardioplegia protective effect onimmature myocardium.Result: Single crystal perfusion high potassium cold bloodcardioplegia group (A) and the routine repeatedly perfusion blood ofcold crystalloid cardioplegia group (B) postoperative atrialnatriuretic peptide, calcitonin gene-related titanium, endothelin, serum creatine kinasecompared with preoperative increasedcompared two groups no significant difference. Electron microscopyof myocardial ultrastructure destruction also has no significantdifferences.