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Study On The Specificity Detection Methods Of Lonicera Japonice Thunb. And Schisandra Chinensis(Turcz.)Baill. In Chinese Patentmedicine And Draft The Standards

Posted on:2016-05-12Degree:MasterType:Thesis
Country:ChinaCandidate:Y ZhuangFull Text:PDF
GTID:2284330464456409Subject:Chinese materia medica
Abstract/Summary:PDF Full Text Request
In recent years, for the protection of traditional authentic ingredients and ensure the effectiveness of the drug, contained ingredients for medicines vary greatly variety of m ulti-source, according to a matter of a principle of China Pharmacopoeia gradually medi cines were the norm, implemented in the pharmacopoeia breakdown.2000 edition of "C hinese Pharmacopoeia" disaggregated varieties Schisandra (Schisandra, Kadsura); 2005 ed ition of "Chinese Pharmacopoeia" disaggregated varieties of honeysuckle (Lonicera, Loni cera). Changes in the source of these species, leading to the use of raw-materials conta ining the above ingredients in some of the more confusing prescription preparations.In this paper, TLC and HPLC-MS method or the like and honeysuckle Lonicera h erbs characteristic components of qualitative research to determine the honeysuckle Loni cera herbs or indicators or characteristic ingredients, build and honeysuckle Lonicera cha racteristic spectrum, distinguish and honeysuckle Lonicera use in prescription formulation s. An Schizandrin again establish proprietary Angola schizandrin TLC for exclusive cont ent, HPLC method of identifying and distinguishing Schisandra Kadsura use in prescripti on formulations. Through the study of herbs collected, establish effective detection meth od to distinguish between the two special properties of herbs, and the method is applie d to the detection of proprietary varieties, according to the relevant pharmacopoeia requi rements, method validation, to ensure accurate and feasible method.In this thesis, varieties of honeysuckle, Schisandra two flavor ingredients and its br eakdown after differences in composition, including how much the presence and content of the ingredients, the establishment of convenient, fast, accurate and exclusive propriet ary analytical methods used to distinguish the easy mixed breed. Optimization, establish common standards applicable to the study of medicine, prescription preparations for the test solution with different processing methods in different premise made using the sa me assay conditions and the techniques to the detection of indicators and detection met hods consistency. Thus be controlled formulations mixed herbs breakdown.
Keywords/Search Tags:Lonicera japonica Thunb., Schisandra chinensis(Turcz.)Baill., Chinese patent medicine, specificity
PDF Full Text Request
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