The Clinical Research Of Tongluo And Inducing Diuresis On Ascites Due To Liver Cirrhosis

Objective:Based on the modern medicine on the comprehensive treatment combined with Tongluo and Inducing diuresis therapy in patients with Ascites due to Liver Cirrhosis, observation of curative effect, to summarize the clinical use of Collaterals treatment efficacy, prove that the collateral disease theory in treating ascites due to cirrhosis in advantage, and explore the mechanism.Methods:Will meet the inclusion criteria of 30 cases with liver cirrhosis were randomly divided into control group and the experimental group, Control group received routine Western Medicine, the treatment group on the basis of conventional therapy of Western medicine combined with traditional Chinese medicine Tongluo and Inducing diuresis treatment, daily 1 agent, taken once in the morning and evening. The two group were treated with 15 days for a course of treatment, according to the prescribed time to record a curative effect observation index, after the end of treatment, each group of cases were treated by statistical TCM symptoms, liver function, hepatic fibrosis index, urine output, abdominal circumference, ascites, and compared, in order to determine the clinical curative effect of Tongluo and Inducing diuresis.Results:After the end of treatment, the total effective rate of treatment group was 86.67%, control group total effective rate was 66.67%, the two groups were compared, P<0.05 had significant difference.Compared before and after treatment, hypochondriac pain, bleeding tendency, teeth bleed at the nose, epistaxis, muscle bleeding,lower extremities weakness, lower extremity pain and numbness, the TCM syndromes have significant difference (P< 0.05), the treatment group was better than that of the control group, after treatment, abdominal swelling, flank rib tingling, dry eyes, dry mouth, red tongue, little ferry, lower extremities weakness, reducing of urine had significant difference (P<0.05), the treatment group was better than that of the control group. After treatment, the symptoms of TCM in the two groups were compared (P<0.05), the treatment group was better than the control group.After treatment, there were significant differences in PTA (P<0.05), the treatment group than the control group; after treatment, the liver function and liver fibrosis had no significant difference (P>0.05), no statistical significance.After treatment, there was significant difference in the changes of body weight, the treatment group than the control group. After treatment, the abdominal circumference, urine volume had significant difference (P<0.05), the treatment group than the control group.After treatment, there was significant difference between the ascites level changes (P<0.05), the treatment group than the control group, there was significant difference; ascites depth (P<0.05), the treatment group was better than that of the control group.Before and after the treatment, the treatment group and the control group had no significant difference in the safety index (P>0.05), no statistical significance.Conclusion:Tongluo and Inducing diuresis have definite clinical effect treatment of ascites due to cirrhosis, can improve the TCM syndrome of patients, reduce the ascites. The long illness into collaterals, disease involving Qi, blood and Body Fluids, The development of the disease to lower jiao is the core pathogenesis of this disease. Tongluo and Inducing diuresis is an important treatment of cirrhosis ascites, worthy of further study.