Heat Transfer Analysis And The Femoral Mechanical Properties Change Of Knee Osteoarthritis Rabbit Under Thermal Environment Of Indoor Sand-therapy

Chronic diseases, including arthritis, lumbocrural pains, cervical spondylosis, etc. will make patients suffer from long-term distress of body and mind. Uyghur medicine sand therapy, a traditional treatment method, has obvious curative effect on these chronic diseases, especially for osteoarthritis(OA). In the recent years, more and more people from home and abroad go to Turpan sand therapy facility for sand treatment because of cognition degree improving of sand treatment in Turpan. But the Turpan traditional Uyghur medicine sand therapy only is implemented in July to September, due to exposed site, strongly influenced by the climate and thermal environment, which greatly limits the extension and application of Uyghur medicine sand therapy.For improving the sand treatment resources utilization, the heat-transfer law and validity of indoor sand treatment must be studied and researched. In the light of the new and effective indoor Uyghur medicine sand therapy method, the indoor sand therapy facility is established. By using the simulated solar heating device, the sand bodies basically achieve the solid temperature. After these procedures, it is to optimize the sand bodies temperature and the heating system, simulate the changes of gas-solid coupling temperature field in natural ventilation of sand therapy room’ individual opening, analyze heat-transfer law of parts of body tissues theoretically and study the changes of mechanical properties of OA rabbit femur in indoor sand treatment experimentally. Specific contents and main results are as follows:(1) In the light of previous experimental datum of Turpan sand therapy facility’ sand bodies temperature in daytime and solar radiation intensity, sand bed temperature will achieve suitable temperature in certain buried deep and the gradient descent distribution trend is basical consistent with the field, after 24 hours of simulating sunlight intensity to heat indoor sand therapy facility.(2) In the process of optimizing the temperature of the sand and sand therapy room heating system, using experimental methods to study the different heating and heat flux changes under heat lamps height, the better way of improving the efficiency of the heating and having the sand layer vertical temperature uniform was elected.(3) The gas-solid coupled thermo-physical model under a single-sided natural ventilation in sand therapy room has been established, the ventilation experiment after heating by simulating sunlight intensity was numerically simulated based on this model. The result of temperature field was calculated and the data of numerical simulation was matched to the experimental date, it Shows reasonable reliability of the model. And ventilation experiment after the heating optimization was numerically simulated on this model too. Suitable for indoor the temperature steady layer and the depth of sand-therapy was obtained by simulating. Through pressing a single-sided natural ventilation, indoor sand-therapy room environment has a certain degree of thermal comfort.(4) A mathematical model was developed here to describe the heat transfer process in rabbit’s body and the sand during the sand therapy. Temperature field was numerically simulated and analyzed based on this model. it has shown that: The blood perfusion played a significant role to maintain a constant temperature for biological tissue temperature,When the thickness of sand was larger than a certain value, the thickness of sand has little effect on the temperature field in the organization of the femur during sand therapy. Temperature filed in biological tissues varied significantly with sand initial temperature, the thickness of sand and sand therapy lasting time, and can be achieved safe and effective hyperthermia temperature and lasting time.(5) The use of the New Zealand rabbits as subjects to study the biomechanics of indoor sand therapy, not only avoids large-scale damage to the human body on CT scan, but also be beneficial to contrast to experimental verification on the further finite element analysis time. It was found that Sand-therapy in Uyghur medicine has benign effect on bone volume of the OA rabbit femur in two ages, and the mechanical properties of the OA rabbit femur in two ages induced by Sand-therapy have increased.