The Study Of Urinary Arsenic And Influencing Factors In Workers Of Arsenic Exposure

Objectives:To detect urinary arsenic content in occupational exposed arsenic in a tin smelter and to analysis the influencing factors of urinary arsenic combined with field investigation.To provide a clue for occupational protection measures of arsenic exposure population.Methods:The subjects of workers were recruited from the factory of tin smelter. Ur inary samples after work of the smelter workers were collected and detected b y wet digestion-hydride-Atomic Fluorescence Spectrophotometry. We designed questionnaire and collected data such as demographic characteristics,life style, the nutrients intake in the last three days, the survey was conducted by face to face. The data was Inputed and consistency checked by software Epidata3.1. Data analysis was used by software SPSSfversion 20.0),We used single factor analysis and two independent samples Logistic regression analysis the influenci ng factors of urinary arsenic.Results:(1) The survey found that the median level of the tin smelter 119 arsenic exposure workers urinary arsenic was 268.34μg/L, The median urinary arsenic contents for male and female were 274.97μg/L,250.01μg/L, respectively. There was no significant difference of median urinary arsenic between male and female.(2) The urinary arsenic were not associated with age (P>0.05) and working age (P>0.05). The urinary arsenic was no significant difference between departments in the smelter (P>0.05). Urinary arsenic was different between ethnic groups, the urinary arsenic of Hani nationality was significantly higher than Han nationality and there was no significant difference between Han and other minorities. There was no significant difference of median urinary arsenic among different education levels (P >0.05).(3) The urinary arsenic was significant difference between different BMI groups. The urinary arsenic of normal group was higher than overweight group,there was no difference between other groups (P>0.05);(4) The survey found that urinary arsenic was no association with Smoke per day and alcohol consumption per day. There was no significant difference between smoking and non-smoking; There was no significant difference between alcohol drinking and non-drinking;(5) Two independent samples Logistic regression analysis showed that the joint action of age, drinking green tea, dietary nutrients intake,such as protein, dietary fiber, vitamin C, niacin, daily protein intake have an effect on urinary. Increasing drinking green tea, dietary fiber, niacin promotes urinary arsenic excretion; but Increasing age, the last three day protein intake, the last three day vitamin C intake, daily protein intake not promotes urinary arsenic excretion;(6) The subjects have poor knowledge of arsenic toxicity, the approaches to arsenic toxic ity is few and far betweea(7) The main clinical symptoms of the tin smelter arsenic exposure workers were neural symptoms and skin lesions,the symptoms were associated with urinary arsenic beyond the standard.Conclusions:(1)Urinary arsenic were not associated with age, working age,smoking per day, alcohol consumption per day; There was no significant difference between urinary arsenic in gender groups, age groups, working age groups, education level groups;(2)There was significant difference among different ethnics, and urinary arsenic in hani group was higher than han groups, There was no significant difference among other groups;(3)Increasing protein,dietary fiber,niacin intake can promote the excretion of urinary arsenic.In a certain extent, increase intake of dietary nutrients can improve the nutritive condition of occupational populations and reduce the health harm effects.(4)This study confirmed that clinical symptoms were followed by chronic arsenic exposure, especially the appearance of the skin lesions, the higher urinary arsenic content, the more obvious clinical manifestations.(5)Chronic arsenic exposure have harm effects on human, expecially skin lesions, the higher level of urinary arsenic, the worse of skin lesions;(6) Whatever arsenic concentration in the working place exceeds the national standards or not, the plant should strengthen monitoring urinary arsenic of occupational population, find high-risk groups and transfer arsenic exposed post; Promoting periodic physical examination and early detect occupational health hazards, treat and change post timely; Improving the nutritive condition of occupation groups such as increase dairy protein, dietary fiber, niacin intake,strengthening physical training.and.enhance.physical.constitution; developing health education and health pr omotion activities actively, enterprise managers need to raise awareness of arsenic toxic ity, enterprise managers perform its duties, enhancing knowledge of occupational diseases prevention and control, increasing means and ways to access to health education knowledge, Increasing understanding of arsenic toxicity occupational groups and self-protection education awareness.