Studies On The Evaluation Of The Hhypolipidemic And Antioxidation Of The Eight Kinds Representative Oat Varieties

In recent years,the hypolipidemic,antioxidant of oat has become a hotspot for research,but most that was concentrated on the research of oat(3-glucan,polyphenols,flavonoids and other active ingredients of a certain function,studies on thehypolipide-micand antioxidation in whole oats were rare.The study of hypolipidemic and antioxidation of oat were evaluated by vitro evaluation system?animal models,and combination of chemical analysis?CAA?animal experiment method.We provided the experimental basis for the further understanding of the effect of hypolipidemic?antioxidation of oats,and also screening excellent oat varieties.Oats component test results show:The contents of RDS?oleic acid?linoleic acid and total polyphenol of the oat named Yanke 1 were the highest,but the content of?-glucan was the lowest.Total amino acids content of Bayou 3 oat was the highest.The contents of crude protein and total flavonoids of the oat named Dingyou 8 were the highest,but the content of Polyphenols was the lowest.Jinyan 14 oat had the highest content.The content of RS of the oat named Linna was the highest,but the contents of total flavonoids and total amino acids were the lowest.The content of linolenic acid of Baiyan 7 oat was the lowest.The contents of RS?oleic acid?linoleic acid of the oat named Bayan 4 were the lowest.By using chemical analysis method and CAA experimental to evaluation the extracts of oats,we found that in the aspect of antioxidant the oat named Yanke 1,Bayou 1 and Dingyou 8 were superior to other oat varieties as a whole.A model of evaluating hypolipidemic effect in HepG2 shows that,the oat named Yanke 1?Jinyan 14?Dingyou 8 extracts in lower the total content of TC effect were better than other oats.The oat named Dingyou 8?Linna and Baiyan 7 extracts in lower the total content of TG effect were better than other oats.Linna and Dingyou 8 oat were superior to other oat varieties in decreasing intracellular IL-8 content aspects.The oats of Bayou 1 oat and Dingyou 8 oat were selected were able to reduce the relative expression of intracellular protein Perilipin and TIP-47.The study used high fat and high cholesterol diet C57BL/6 male mouses model to evaluate the hypolipidemic and antioxidant effects of the oat extracts.The results showed that:oats has a positive effect on the routine index,liver index and serum index of mice.Among them,the oat named Yanke 1?Bayan 4 were significantly better than the other 5 variaties in the control of body weight and maintaining the normal metabolism of the liver of C57BL/6 male mice.The oat named Linna?Yanke 1 oat varieties had certain advantages in reducing the blood lipid of C57BL/6 male mices.The oat named Bayou 3?Yanke 1?Dingyou 8 were significantly better than the other varieties in the aspects of antioxidant of the C57BL/6 male mice.At last,we selectd Yanke 1?Dingyou 8 oats as the antioxidation good varieties,and selectd Linna?Yanke 1 oats as the hypolipidemic good varieties.