Zuo Zhensu's "Wet Phlegm And Blood Stasis" Academic Thought And Clinical Research On Treating Alcoholic Fatty Liver From "Wet Phlegm And Blood Stasis"

Mentor Zuo Zhensu, director of Chinese medicine practitioners, the fourth, five group of the old Chinese medicine experts in the academic thought inheritance to guide the work of the teacher, in Shandong Province Traditional Chinese medicine experts, the doctor of traditional Chinese medicine talents guidance teacher, master tutor. Engaged in medical, teaching, research in the past forty years, she has always been a big doctor for the motto, to guide their practice of practice medicine. Its academic thoughts and clinical experience is a very precious wealth of traditional Chinese medicine. These theories and experiences should be summarized. Through the systematic collection and collation of the experience of the clinical experience of the Chinese medicine in the Department of internal medicine of TCM, the thesis focuses on the treatment of diseases such as the teacher's good treatment, and summarizes the academic thought and experience. In particular, the application of the teacher's "wet phlegm and blood stasis" pathogenic academic thought as the guide, to prevent AFL in a comprehensive summary of research. On the one hand, the academic thought and clinical experience of the tutor can be kept and inherited, but also it has a more practical guidance significance to the medical department of internal medicine.This thesis is divided into three parts: the academic origin of the tutor and the analysis of various theories, the academic thought and clinical experience of the mentor, the clinical research.Part 1: The academic origin of the tutor and the analysis of various theories. Depth profiling of mentor's academic origin, at the same time, briefly contemporary physicians such as Deng Tietao, Zhu Liangchun famous doctors “wet phlegm and Blood Stasis” Theory, put forward the insights and perspectives.The second part: The research on the academic thought and clinical experience of tutor. This topic through three years with the division of clinical large collection, finishing Zuo Zhensu director physician, teach, research and clinical success cases and academic monographs, academic thought and clinical experience for the main vein, collect, collate, summarize the tutor specializes in treating diseases such as non-AFL, gout, rheumatoid arthritis disease and the basic theory of TCM, experience, calcite and its clinical application. Especially on alcoholic fatty liver to do further clinical studies, refine the tutor theory essence of Chinese Medicine Department of internal medicine.Part III: Clinical study of tutor academic thought- from "wet phlegm and blood stasis" On the clinical research treatment of AFL. First,overview. Is "alcoholic fatty liver research progress", from the aspects of the name of disease, etiology and pathogenesis, treatment prescriptions, systematically reviews the research situation of TCM in nearly ten years in alcoholic fatty liver, and has made the detailed summary on alcoholic fatty liver and pathogenesis research situation and on the problems existing in present study and insufficient and future development direction and the prospect of do briefly. Second,clinical research. Objective:Summarized professor Zuo Zhensu's "wet phlegm and blood stasis" pathogenic academic thoughts and clinical experience, and from "wet phlegm and blood stasis" differentiation, observation the clinical efficacy and safety of Juanzhifang in treatment of Alcoholic Fatty Liver. Methods: AFL patients in remission 60 patients met the inclusion criteria, were randomly divided into two groups: the control group of 30 patients, given silybin oral, 70mg/3 times a day; Test group of 30 patients, on the treatment from “wet phlegm and blood stasis”, given Juanzhifang oral, one day.A course of four weeks, starting the next course of treatment after the interval of 2 days, patients were treated for 3 courses, After the treatment, the clinical efficacy and clinical efficacy of TCM symptoms in the two groups were compared, and the results were analyzed. Results: After the treatment, comprehensive curative effect, treatment group total effective rate was 93.333%, the control group was 76.667%, the difference was statistically significant(P<0.05); Group of TCM syndrome curative effect of the total effective rate was 83.333%, the control group was 60.000%, the difference was statistically significant(P<0.05); Experimental group on the right side and unwell/home/pain/tingling, often boring abdominal distension, weakness, fatigue, and god for the improvement of symptoms were better than control group(P<0.05); Group of ALT, AST, GGT, TG, CHO effect and ultrasound disease curative effect is superior to the control group(P<0.05); Two groups of treatment, no adverse reactions occurred after the end of review safety indexes in the normal range. Conclusion: "Wet phlegm and blood stasis" is the important pathogenesis of AFL, Juanzhifang is to improve the condition of patients with alcoholic fatty liver and effective prescription to improve the quality of survival, its curative effect is distinct, security is good,worth popularizing.