Clinical Observation Of Effect Of The Method Of Soothing Liver And Regulating Qi On The Liver Qi Stagnation With Functional Dyspepsia Epigastric Pain Syndrome

Objective:This clinical trial is used to evaluate the effect of the method of soothing the liver and regulating Qi on Epigastric Pain Syndrome with a syndrome of stagnation of liver Qi.By the trial,we observe the clinical effect of soothing the liver and regulating Qi and analyzed the action mechanism of the herbs which could provide the rules of syndrome differenciation and the usage characteristics of herbs.Methods:In this study,randomized controlled methodology was used to study the patients from department of spleen and stomach of Jiangsu Provincial Hospital of Chinese Medicine.A number of 60 patients who were diagnosed with Epigastric Pain Syndrome also met the standard of liver depression syndrome.All the patients were randomly divided into two groups,treatment group and controlled group,with 30 patients of each group.There is no significant difference between the two groups in terms of their age,gender,condition before treatment.The patients of treatment group were treated with mothed of soothing the liver and regulating Qi,while those of the controlled group were treated with Omeprazole Enteric-coated Capsules.4 weeks were set as a course of medication,during which patients from both groups were treated.Patients' symptoms scores change before and after treatment are observed and the comparison was made between the two groups and the data from the trial by the statistics mothed were analysed to find the rule of the syndrome differenciation and characteristics of the herbs.Results:1.total clinical effect:Total clinical effect of the treatment group is 96.67%while the controlled group is 80.00%which the difference between the two groups is significant(P<0.01).The result show the effect of treatment group is better than that of the controlled group.2.comparison of total score of symptoms between the two group:The difference of the total score between the two groups' symptoms is statistically significant(P<0.01)which could imply the two group all had a improvement after the usage of medication while the treatment group has a better effect than the controlled group.3Comparison of the individual score of symptoms between the two group:(1)The treatment group had a good effect in improvement of the symptoms of epigastric pain,burning sensation of upper abdomen,acid regurgitation,abdomen distension,epigastric fullness,belching and irritability(P<0.01);The control grouphad a good effect in improvement of the symptoms of epigastric pain,burning sensation of upper abdomen,acid regurgitation,abdomen distension,epigastric fullness(P<0.01)except belching and irritability(P>0.05).(2)The effect of treatment group is more better than controlled group on belching,irritability and abdomen distension(P<0.01),The effect of treatment group is better than controlled group on epigastric pain(P<0.05),the treatment group and the control group had the same effect on burning sensation of upper abdomen,acid regurgitation and epigastric fullness(P>0.05).Conclusion:Method Soothing liver and regulating Qi has a good clinical efficacy on the liver Qi stagnation syndrome with Epigastric Pain Syndrome.It can effectively relieve the symptoms caused by Epigastric Pain Syndrome and has no side effect.The result of the trial indicates that the method of soothing liver and regulating Qi is an effective treatment for Epigastric Pain Syndrome which is worthy of further study and promotion.