| Objective The purpose of this study was to observe the clinical efficacy of analgesic decoction for the treatment of chronic erosive gastritis,and discusses the characteristics and mechanism of analgesic soup and its mechanism,modern pharmacological research and so on.In order to carry forward the name of famous doctors,this paper provides a theoretical basis for the treatment of erosive gastritis.Method Randomly selected 90 patients by electronic gastroscope examination for chronic erosive gastritis,TCM syndrome differentiation is blood stasis stop stomach type.With Chinese medicine outpatient service,visits and detailed record of the patient's age,gender and so on general situation and the course of the disease.The 90 cases were randomly divided into observation group and control group,48 cases were observed in the observation group and 2 cases were shed.In the control group,there were 42 cases and 3 cases were shed.There was no statistically significant difference between the two groups in general,course of disease,and endoscopic classification(P<0.05).The observation group was treated with traditional Chinese medicine analgesic decoction,daily dose,before morning and evening meal.The control group was treated with the treatment of 40 mg bid with the western drug pantoprazole sodium enteric capsule.The total treatment course was 6 weeks.Ask the two groups of patients in the treatment process note diet,rest,put an end to alcohol,tobacco,try to keep emotional stability and avoid strenuous exercise,are not allowed to take may have an impact on the disease or the test result of other drugs.Blood analysis,urine analysis,stool examination,liver and kidney function and ecg examination were needed for 1 week before and after treatment.By TCM physician visits to patients,in the form of clinical symptom score,at the same time on two groups of symptoms improve the situation,the total effective rate,the result of endoscopic,relapse,such as safety index is analyzed,compared two groups of drugs and treatment effect and the curative effect of security.Results The study data showed that:(1)After 6 weeks of treatment,14 patients in the observation group were cured clinically,18 were effective,11 were effective,3 were ineffective,and the total effective rate was 93.48%.Among the 39 cases in the control group,11 were cured clinically,14 were effective,10 were effective,4 were ineffective,and the total effective rate was 89.74%.The total effective rate of the observation group and the control group after treatment was statistically different(P<0.05).(2)After 6 weeks of treatment,the symptoms of two groups were significantly lower than before treatment symptoms integral,there are significant difference statistically significant(P<0.01),the observation group after treatment compared with the control group after treatment of clinical symptoms integral statistically significant(P<0.05).(3)The electronic gastroscopy results of the two groups before and after treatment: observation group before the treatment,there is 0 cases in 0 level,15 cases in ?level,13 cases in ? level,18 cases in ? level;6 weeks after treatment,there is 2 cases in level 0,14 cases in?level,18 cases in ?level,12 cases in ? level.The control group before treatment: there is 0 cases in level 0,13 cases in?level,14 cases in ?level,12 cases in ? level;6 weeks after treatment,there is 1 case in level 0,14 cases in?level,16 cases in ? level,8 cases in ? level.There was no statistical difference between the two groups after treatment(P>0.05).(4)4 weeks after the end of treatment in the two groups,13 patients in the observation group were cured,18 were effective,12 were effective,3 were ineffective,and the total effective rate was 93.48%.In the control group,10 cases were cured,13 cases were effective,11 cases were effective,5 cases were ineffective,and the total effective rate was 87.18%.The total effective rate was statistically different(P<0.05),and the recurrence rate of the observation group was significantly lower than that of the control group.No significant adverse events occurred in the observation group and the control group during the whole treatment process.Blood analysis,urine analysis,fecal examination,liver and kidney function and electrocardiogram were reviewed 1 week after the end of treatment,showing normal range and no significant change before the study.It is proved to be safe and reliable.Conclusions Analgesic decoction can significantly improve the clinical symptoms and physical signs of patients with chronic erosive gastritis with blood stasis and gastric cessation,and which is superior to western medicine-pantoprazole sodium enteric-dissolution capsule.In the long-term effect,analgesic soup recurrence rate is lower.No obvious adverse reactions were observed during the treatment,and the safety was reliable.However,analgesic decoction has no obvious improvement in endoscopic manifestations and endoscopic grading of erosive gastritis,which requires further improvement and optimization. |
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