Font Size: a A A

A Retrospective Analysis Of Chinese And Western Medicine In The Treatment Of Breast Cancer During The 5 Years

Posted on:2019-05-18Degree:MasterType:Thesis
Country:ChinaCandidate:Q BaoFull Text:PDF
GTID:2334330545983285Subject:Integrated Traditional Chinese and Western Medicine in Oncology
Abstract/Summary:PDF Full Text Request
Objective:According to January 2013--December 2017,233 case s of breast cancer women diagnosed and treated in the departmen t of oncology and breast surgery of Chinese and western medicin e in wuhan city were diagnosed and treated.Its main retrospecti vely analyzed the breast cancer patients in general information,pathologic type,disease stage,immunohistochemical(ER,PR,Her-2,K i-67),molecular classification,risk classification,dialectical traditional Chinese medicine,traditional Chinese and western me dicine treatment,the effect of traditional Chinese and western medicine treatment and relapse metastasis,recurrence,transfer n umber of organs,survival rate,overall survival and disease-free survival,inductive analysis it is concluded that the effective ness of all kinds of Chinese and western medicine treatment of breast cancer,the factors affecting area of recurrence of breas t cancer metastasis and the number of organs,and at the same ti me from two aspects of Chinese and western medicine analysis OS(overall survival)and the influence of female breast cancer DFS(disease-free survival)risk factors.Method:Research and analysis the clinical data of patientswith breast cancer characteristics,refer to cases,the collected data for processing,EpiData database of the input,then use SPS S 22.0 statistical software for statistical data analysis,the c linical and pathological data to Cox proportional hazards model with single factor(the study of the relationship between the f actors and breast cancer)and various factors(control other inf luencing factors,a kind of research the relationship between fa ctors and breast cancer)analysis,HR and 95% CI.All data were st atistically significant with P<0.05.Result:The three kinds of traditional Chinese medicine trea tment compared with each other,one is traditional,earpins soak+Chinese medicine external treatment+traditional Chinese medicin e acupuncture less patients with disease progression,treatment effect has a significant difference(P<0.05).The diagnosis of b reast cancer age,pathological type,TNM staging,ER/PR,molecular classification,Chinese medicine dialectical classification are not statistically significant(P>0.05),temporarily cannot prov e that number about the site and transfer and transfer of organ s;Her-2 expression positive patients,Her-2 cases of bone metast ases is less than Her-2 only to express negative,positive patie nts with distant metastasis and Her-2 expression more cases tha n Her-2 expressing negatie,to prove that Her-2 expression and metastasis of breast cancer site differences statistically sign ificant(P<0.05);There were fewer cases of pure bone metastasis in patients with overexpression of her-2,significantly lower t han the other four types,and the results were statistically sig nificant(P<0.05);The transfer of risk for patients with interm ediate and high number of organs compared to patients with breast cancer risk in a low is on the high side,to prove that the r isk of breast cancer grading and transfer of organs number diff erences statistically significant(P<0.05).OS Cox regression in the single factor analysis of breast cancer diagnosed age,fami ly history,pathological type,T stage,N stage,regional lymph nod e metastasis,ER/PR,transfer,transfer number of organs for the f actors influencing the risk of breast cancer patients' overall s urvival,results are statistically significant(P<0.05);Multiple factors analysis,family history,T stage,N stage,regional lymph node metastasis,ER/PR number and transfer of organs for the fa ctors influencing the risk of breast cancer patients' overall su rvival,results are statistically significant(P<0.05);Breast ca ncer DFS Cox regression in the single factor analysis,T and N s tage,ER/PR,Her-2 expression and risk,transfer,transfer number o f organs for impact disease-free surial in patients with breast cancer risk factors,the results statistically significant(P<0.05);The family history,TN stage,ER/PR,and number of metastatic organs were the risk factors for the disease-free survival per iod of breast cancer patients,and the results were statisticall y significant(P<0.05).Conclusion:Her-2 expression positive,Her-2 overexpression,r isk classification for intermediate or high possibility of recu rrence of breast cancer patients transfer is higher,in determin ing the integrated traditional Chinese medicine and western med icine,can choose the treatment of high strength;Between January2013 and December 2017,our hospital of Chinese and western me dicine treatment of breast cancer patients 1 year,3 years,5 y ears survival rates were 98.7%,92.9%,84.1%,better than single western medicine treatment of survival international level;Di agnosis were 41,have a family history,TN staging later,ER/PR(+/-+/---),OS with recurrence,metastasis of breast cancer risk f actors,family history,TN staging later,ER/PR(-),Her-2 expressio n positive and high risk classification,risk factor for recurre nce metastasis DFS in breast cancer patients.
Keywords/Search Tags:Breast cancer, Chinese and western medicine treatment, Recurrent metastasis, Survival period, Retrospective analysis
PDF Full Text Request
Related items