Study On Characteristics Of TCM Syndrome Types Of Proteinuria In Chronic Primary Glomerulonephritis

Objective:The research tries to start with proteinuria,to study on TCM Syndrome characteristics of proteinuria in patients with chronic Primary Glomerulonephritis,to analyse the main types of proteinuria,then to obtain the correlation of the main deficiency syndrome type and clinical general data(sex,age,course of disease,systolic pressure,diastolic pressure,etc.),every sign and laboratory index(Hb,ALb,Scr,Cys-c,β2 microglobulin etc.),And then to guide the microscopic differentiation of proteinuria.In order to treat chronic glomerulonephritis proteinuria for patients with chronic glomerulonephritis,and it provides some objective basis for reference value in addition to the traditional syndrome differentiation method,which is conducive to the treatment of diseases early.Methods:The clinical data of 131 patients with chronic glomerulonephritis who Compliance with inclusion criteria in order to make the table about Chronic Glomerulonephritis Case Observation,including general information(age,sex,course of disease,blood pressure and clinical symptoms of the patient)and laboratory findings(urinary protein quantification in 24 hours,Hb,Alb,Scr,BUN,Cys-c,β2 microglobulin,CKD staging,D2 Polymer,TG,urinary Microalbumin,urinary Prol,urinary BLD),which is grouping by 24 hours urinary protein.Group A ≥0.15g/24 h and < 1 g / 24 h;Group B≥1g/24 h and < 2g /24 h;Group≥2g/24 h and < 3.5 g/24 h,then TCM syndrome differentiation was carried out according to "chronic glomerulonephritis diagnosis,syndrome differentiation and evaluation criteria in 2006",and applying SPSS 20.0 software for statistical treatment of relevant data,with P < 0.05 was statistically significant as the difference.Results:1.There was a correlation between CKD staging and CGN in different proteinuria groups in ages,sex,and CKD staging.2.The most frequent symptoms of frequency twelve were mild and moderate symptoms,and severe symptoms were rare in the 131 cases of CGN.3.The syndrome differentiation was based on deficiency and standard in 131 patients with CGN in the 131 patients with CGN,in which deficiency of spleen and kidney qi was the more common syndrome in group A,and in Group B,deficiency of Qi and Yin was more common in both syndromes and syndromes.In group C,spleen and kidney yang deficiency were the more common syndromes.The syndrome of dampness and heat was easy to be clamped in the three groups of proteinuria,the syndrome of blood stasis was easy to be clamped in group B,and the syndrome of dampness and turbid blood stasis was easy to be clamped in group C.4.The course of the CGN patients with different proteinuria has a correlation with the main TCM syndromes in hypertension and course of disease distribution,that is,with the increase of proteinuria and the change of TCM syndrome type,the course of disease becomes shorter.5.The main TCM Syndromes of CGN patients with different albuminuria were associated with Alb,β2 microglobulin,Cys-c,CKD staging,urine microalbuminuria,urinary occult blood and urinary protein.(1).The results of the examination of Cys-c and β2 microglobulin in group B were significantly higher than those in the same group and the same group,and the difference was statistically significant.(2).The results of HB examination in group C were higher than those in the same group,and the difference was statistically significant.(3).CKD1 stage was more common in group A in CKD staging.CKD2 stage is more common in group B.CKD3 stage is more common in group C.(4).In urine examination,urinary microalbumin was most likely to be detected in group A,urine PRO 1 + and urine BLD +-were used at the same time.In group B,urine pro 2 and BLD1 were more common.In group C,urine pro 3 and BLD 2 were more common.Conclusions:1.CKD staging and CGN patients with different proteinuria is corrective.2.In CGN proteinuria patients,syndrome differentiation is mainly based on deficiency of essence and standard in group A.In Group B,deficiency of Qi and Yin was more common in both syndromes and syndromes.In group C,spleen and kidney yang deficiency are common syndromes.In the three main phases,damp heat syndrome is more common,which isuggests that damp heat runs through this disease.And it is the key factor to cause kidney damage.What’s more,with the progress of the disease and the increase of the degree of proteinuria,the main demonstration is blood stasis syndrome,wet turbid and blood stasis syndrome.3.In the course of the disease,CKD stage,Alb Cys-c,β 2 microglobulin,urinary microalbumin,urine occult blood and urine pro are correlated with the main TCM syndromes of CGN patients in different proteinuria groups.It can provide certain reference basis for TCM syndrome differentiation and treatment.