Application Of Drug Coated Balloon In Restenosis After Coronary Artery Stenting

Objective: The efficacy and safety of drug coated balloon and drug-eluting stent in the treatment of patients with stent restenosis were compared and analyzed.Methods:From January 2015 to December 2016 in the heart center of the First Affiliated Hospital of Xinjiang Medical University medical PCI after surgery,the chest pain,chest tightness,once again our hospital coronary angiography in patients with in stent restenosis,were randomly divided into treatment group and drug coated balloon drug-eluting stent in the treatment group.The balloon group was treated with paclitaxel to release the coronary balloon,and the stent group was treated with Abbott eluting stent.The follow-up was 8-12 months after the operation.To observe the incidence of major cardiac adverse events of two groups of patients,thrombosis rate and reference vessel diameter,minimal lumen diameter,lesion length,inner stent late lumen loss.Results:In the final balloon treatment group,29 patients were included in the treatment group.The stent treatment group was included in the statistical analysis of 28 patients.The general data of the two groups were the same and the baseline was consistent.After balloon group stent stenosis was higher(10.3±9.4% vs.10±9.6%,P=0.515);group after balloon stent minimal lumen diameter is smaller(2.49±0.44 mm vs.2.53±0.42 mm,P=0.742);but no statistical difference(P<0.05),after 8-12 months coronary angiography outcome measures:the treatment group was higher than that of the reference vessel diameter balloon stent in the treatment group,the difference was not statistically significant(P>0.05);the treatment group is lower than the minimal lumen diameter balloon stent in the treatment group,the difference was not statistically significant(P>0.05).The stenosis rate of the balloon group was lower than that of the stent group(P>0.05),and the late lumen lost balloon treatment group was higher than that of the stent group(P>0.05).The rate of restenosis in stent group was higher than that of balloon group(P < 0.05)was statistically significant,thetreatment group did not occur during follow-up balloon cardiovascular events and stent thrombosis,incidence of acute myocardial infarction in 2 cases treated with PCI,1patients with in stent thrombosis occurred 7 days after operation,the incidence rates were0% and 7.1% the major adverse cardiac event,there was no statistically significant difference(P>0.05).The thrombus formation rate was 0% in the balloon treatment group and 3.5% in the stent group,but the difference was not statistically significant(P>0.05).Conclusion: Drug coated balloon and drug-eluting stents can effectively treat in stent restenosis.Drug-coated balloon is superior to drug-eluting stent in efficacy and safety.