| Objective:To observe the clinical efficacy and safety of chest stuffiness and pains ointment in the treatment of stable angina pectoris of coronary heart disease.Methods:A total of 72 patients admitted to the department of cardiology of the affiliated hospital of gansu university of traditional Chinese medicine were selected from January 2017 to December 2017,the random number table method was divided into two groups,and 36 patients in the control group and the treatment group,the control group was treated with traditional western medicine,and the treatment group was applied to the traditional western medicine,each time 10 g,2times a day,the course of treatment is 8 weeks.The SAQ scores of patients before and after treatment were observed,the total score and efficacy of TCM syndromes,the reduction rate of nitroglycerin,the efficacy of electrocardiogram,Duke score,Hcy and lipid level.SPSS20.0 software was used for statistical analysis.Results:1.There was no significant difference in baseline date between the two groups before treatment(P>0.05).2.SAQ scores and differences comparison: in both groups before and after treatment in both groups each entry score and difference comparative differences are statistically significant(P<0.05),and the treatment group after treatment increase each item scores than the control group(P<0.05).3.Comparison of total score and difference of TCM syndrome in two groups of patients:The total score and difference between the two groups of patients before and after treatment were statistically significant(P<0.05),and the total reduction of TCM syndrome after treatment was greater than that of the control group(P<0.05).4.Comparison of efficacy of TCM syndromes in two groups of patients:The difference between the two groups was statistically significant(P<0.05),and the total effective rate of treatment group(91.7%)was higher than that in the control group(72.3%)(P<0.05).5.The rate of nitroglycerin reduction was compared between the two groups:Thedifference in the rate of nitroglycerin reduction in the two groups was statistically significant(P<0.05),and the rate of nitroglycerin withdrawal in the treatment group(83.3%)was higher than that in the control group(61.1%)(P<0.05).6.Comparison of ECG in the two groups:The difference of electrocardiogram efficacy between the two groups was statistically significant(P<0.05),and the total effective rate of the treatment group(63.9%)was higher than that of the control group(41.7%)(P<0.05).7.Comparison of Duke and difference between two the groups:The difference of Duke score and difference between the two groups was statistically significant before and after treatment(P<0.05),and the increase of Duke score in the treatment group was greater than than that of the control group(P<0.05).8.Comparison of serum lipid level and difference between the two groups:The difference of blood lipid level and difference between the two groups was statistically significant(P<0.05),and the treatment group TC,TG and LDL-C decreased significantly more than the control group(P<0.05),and the increase of HDL-C was greater than that of the control group(P<0.05).9.Comparison of Hcy level and difference between the two groups:The difference of Hcy level between the two groups was statistically significant before and after treatment(P<0.05),but there was no statistically significant difference between Hcy and control group after treatment(P>0.05).10.Security results:There was no significant difference between blood,urine,fecal routine,liver and kidney work and coagulation group(P>0.05).Conclusion:For coronary heart disease stable angina pectoris(Phlegm Stagnation and Blood Stasis)treatment of patients with obstruction of heartache cream combined western medicine group is better than pure western medicine group,its performance in improving patients with TCM syndrome,electrocardiogram ischemic changes,blood lipid level and improve the quality of life,exercise tolerance. |
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