Nutritional Evaluation Of 96 Patients With Inflammatory Bowel Disease

Background Malnutrition is one of the most common complications of inflammatory bowel disease.The main causes of malnutrition are insufficient intake of nutrients,loss of nutrition due to gastrointestinal absorption dysfunction,effects of drugs and inflammation.Therefore,many nutritional associations recommend using the rapid nutritional risk screening scale 2002 to assess the nutritional risk in patients with IBD,and giving the early nutritional intervention in patients with malnutrition.Objective1.To assess the malnutritional risk of IBD patients via NRS 2002 scale and PG-SGA scale;Analyzing the effects of different influential factors on nutritional evaluation.2.To evaluate the risk factors of malnutrition in IBD patients.Method1.The study involved in 96 IBD patients from specific institution.2.The data was analysed by statistical software.Results1.56 patients were at a high risk of malnutrition,with an average age of 44.07±15.77 years and an average hospital day of 15.36±7.16 days,40 cases of UC,16 cases of CD;37 cases without corticosteroids therapy now,19 cases with corticosteroids therapy now.40 patients were at a low risk of malnutrition,with an average age of 21.28±14.2 years and an average hospital day of 11.05±6.42 days,21 cases of UC,19 cases of CD;37 cases without corticosteroids therapy now,3 cases with corticosteroids therapy now.The malnutrition incidence of patients with characteristics of severe ulcerative colitis,female,older,under corticosteroids therapy now was significantly higher than that of moderate and mild ulcerative colitis,male,younger and without corticosteroids therapy group(P<0.05).2.56 cases with a higher risk of malnutrition presented with CRP status of 3.44±3.29mg/dl ESR status of 38.45 ± 13.68mm/h;40 cases with a lower risk of malnutrition presented with CRP status of 1.26±2.82mg/dl and an ESR status of 21.28±14.20mm/h;Patients with higher inflammation-associated markers presented with higher malnutritional risk(P<0.05).3.44 cases of the 96 patients were diagnosed as anemia,only 21 cases underwent relevant inspections and 13 of them were diagnosed as iron-deficiency anemia.8 cases received iron supplement therapy.4.56 cases with a higher risk of malnutrition,12 cases did not receive nutrition support therapy,44 cases received nutrition support therapy;40 cases with a lower risk of malnutrition,20 cases did not receive nutrition support therapy,20 cases received nutrition support therapy;Patients with higher malnutritional risk have a higher proportion of using nutritional support therapy(P=0.003).Conclusions: 1.The malnutrition incidence of patients with characteristics of severe ulcerative colitis and inflammation-associated markers,female,older,under corticosteroids therapy now are higher than that of without these characteristics.2.There are still some patients with nutritional risk do not receive nutrition-support treatment.3.Anemia is a common complication of patients with IBD.Iron deficiency anemia and chronic anemia are the main types of anemia in IBD patients.However,there are still many patients with iron deficiency anemia do not receive iron supplementation.Therefore,as for the IBD patients with anemia,it is necessary for clinicians to make relevant examinations to clear the cause of anemia and perform iron supplementation therapy if necessary.