Clinical Observation On Treatment Of Hypomenorrhea Of Thin Endometrium Of Kidney Deficiency And Blood Stasis Syndrome By Internal And External Therapy

[Objective] To observe the clinical curative effect of patients with hypomenorrhea of thin endometrium of kidney deficiency and blood stasis syndrome by using oral Chinese medicine,oral Chinese medicine combined with external treatment and oral Bujiale+progesterone soft capsule,and to evaluate the comprehensive curative effect of oral Chinese medicine and internal and external treatment,so as to provide more treatment ideas for this disease.[Method]124 cases of thin endometrium of kidney deficiency and blood stasis syndrome with hypomenorrhea were collected and divided into three groups according to the principle of random distribution.Treatment group 1(n = 40),oral Bushen Huoxue Decoction plus subtraction;treatment group 2(n = 42),oral Bushen Huoxue Decoction plus sitting moxibustion therapy;control group(n = 42),oral Bujiale + progesterone soft capsule.After 3 months of treatment,the clinical symptoms and signs,menstrual volume,endometrial thickness,meridian chromoplasm,blood loss score and blood estradiol(E2)value were observed before and after treatment in three groups,so as to analyze the clinical efficacy of three methods in treating thin endometrial hypomenorrhea of kidney deficiency and blood stasis syndrome.[result]1.Compare the comprehensive curative effect of three groups: the total curative effect of treatment group 1,treatment group 2 and control group were 77.5%,85.0% and 90.0%,respectively.The clinical curative effect of treatment group 2 and control group was better than that of treatment group 1(P=0.006 < 0.05).2.Comparing the therapeutic effect of three groups,the main symptoms,intima thickness and menstrual volume: treatment group 2 and treatment group 1(P < 0.05),control group and treatment group 1(P < 0.05)have significant differences,indicating that treatment group 2,control group improve the main symptoms,intima thickness,menstrual volume curative effect is better than treatment group 1;comparison of secondary symptoms,menstrual color quality: treatment group 1 and control group 1(P < 0.05),treatment group 2 and control group(P < 0.05).There were significant differences between the treatment group 1 and the treatment group 2 in improving secondary symptoms and meridian chroma;E2 value: There were significant differences between the treatment group 1 and the control group(P < 0.05),the treatment group 2 and the control group(P < 0.05),and the control group was better than the treatment group 1 and 2 in improving the level of E2 in vivo;the amount of residual blood loss was compared between the treatment group 1 and the treatment group 2(P < 0.05).There was significant difference between the control group and the treatment group 2(P < 0.05),which indicated that the treatment group 2 was better than the treatment group 1 and the control group in improving the amount of lost blood clots;there was significant difference between the treatment group 1 and the treatment group 2(P < 0.05),indicating that the treatment group 2 was better than the treatment group 1 in improving the total symptoms.3.There were significant differences in the main symptoms,secondary symptoms,loss of blood clots,total score,intima thickness,menstrual volume,meridian chroma score and E2 value between the three groups before and after treatment(P < 0.05).[Conclusion] 1.Comparisons before and after treatment in the three groups can effectively improve the main symptoms,secondary symptoms,loss of blood clots,total score,intima thickness,menstrual volume,meridian color quality score and E2 value.2.Improvement of E2 level: The control group was significantly better than the treatment group 1 and 2;3.Em improvement: treatment group 2 and control group can achieve better results.4.Improvement of comprehensive curative effect: The treatment group 1 oral Bushen Huoxue Decoction can effectively treat symptoms and signs of patients with thin endometrial hypomenorrhea of kidney deficiency and blood stasis syndrome.The treatment group 2 combined with external treatment of sitting moxibustion apparatus can play a synergistic role,not only can further improve the clinical efficacy,but also can effectively improve the accompanying symptoms of traditional Chinese medicine.There was no significant difference between the treatment group 2 and the control group in the treatment of the disease.However,there was no obvious contraindication between the internal and external therapies in the clinical practice and the applicable population was wider.Therefore,it could be used as a better alternative therapy for those who were not suitable for the application of bugalore or who were not effective in taking observation dosage of bugalore and were unwilling to increase hormone dosage.