| Objective: The main purpose of this study is to investigate the treatment of chronic cough by means of dispelling wind and relieving spasm,promoting blood circulation to remove meridian obstruction,invigorating the spleen to eliminate dampness,activating blood circulation to dissipate blood stasis,relieving the depressed liver,Regulating Qi and activating blood circulation,or Yi qi gu ben,Broken blood stasis.The efficacy and reliability of treating chronic cough by clinical comparison of curative effect,cough degree and symptom score were discussed.It provides new thinking and dialectical basis for the clinical treatment of chronic cough dialectically,so as to improve the therapeutic effect of chronic cough.Method: 120 cases of respiratory department outpatients in Jingzhou city hospital of TCM from September 2016 to December 2017,who met the inclusion criteria were selected for observation.They were randomly divided into a treatment group and a control group with60 cases in each group?Among them,32 males and 28 females in the treatment group,with an average age of 36.66 + 8.02 years,had a disease course of 8-16 weeks and an average course of disease(62.12+ 2.22)days.There were 3 cases of abscission in the treatment group.There were 29 males and 31 females in the control group,with an average age of 34.24 + 9.33 years,a disease course of 8-16 weeks and an average course of disease(61.44 + 2.78)days.The control group had 4 cases of abscission.There was no statistically significant difference between the two groups in gender,age and course of disease(P > 0.05).The treatment group was treated with compound methoxyphenamine capsule combined with TCM,and the control group was mainly treated with compound methoxyphenamine capsule.According to the dialectic of Chinese medicine,the treatment group was divided into four types: wind-evil Invading lung,turbid phlegm obstructing lung,liver fire invading lung,lung and spleen qi deficiency and dialectically administer drugs according to the 4 types of different pathogenesis.The two groups were treated for 10 days.During the treatment,patients' symptom changes and adverse drug reactions were closely observed,and clinical observation was excluded for some patients with poor compliance or with obvious adverse drug reactions.At the end of treatment,the therapeutic effect,cough visual score,symptom improvement time and symptom score were compared.And analyze the statistics with statistical software.Result: By comparing the total curative effect between the two groups,there were 3 cases of abscission in the treatment group,the total effective rate was 91.2% in 57 cases,and 5 of them are invalid.In the control group,there were 4 cases of abscission,9 cases of inefficacy,and the total effective rate was 83.9%.By rank sum test,P<0.05 showed significant difference in therapeutic effect between the two groups,indicating that the total therapeutic effect of the treatment group was better than that of the control group.There was no significant difference between the two groups in VAS score before treatment compared with P >0.05,so they have comparability.The comparison between the two groups after treatment and before treatment,P < 0.05,was statistically significant.It indicated that both groups of treatment can improve chronic cough symptoms.However,VAS scores of the two groups were compared after treatment was P< 0.05,there was a significant difference.The results after treatment of two groups indicated that the VAS score of the treatment group was significantly better than that of the control group.Because of P > 0.05 after t test,there was no significant difference between the two groups in the score of each single symptom before treatment,so there was comparability between the two groups in the score of single symptom.T test was used to compare the score of symptoms between the two groups before and after treatment,and P < 0.05 was statistically analyzed,indicating that both groups could improve the patient's symptoms.After treatment,the symptom score of the treatment group and the control group was tested by t test,and the result of statistical analysis was P < 0.05,which has statistical significance,indicating that the treatment group was superior to the control group in improving the symptom score.The total TCM syndromes score of the two groups before treatment was tested by t test,and P > 0.05 was statistically analyzed,showing no significant difference and comparability.After treatment,the total score of TCM syndromes was tested by t test,and P < 0.05 was statistically significant.It indicated that the treatment group was superior to the control group in improving TCM syndromes.T test was performed at the the effect-acting period in the two groups,and P < 0.05 was statistically significant.T test was adopted for the two groups of treatment courses,and statistical analysis showed that P < 0.05 was of statistical significance.The comparison showed that the effective time of the treatment group was significantly faster than that of the control group,and the total course of treatment in the treatment group was significantly shorter than that of the control group. |
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